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Fenobam [N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea] is an atypical anxiolytic agent with unknown molecular target that has previously been demonstrated both in rodents(More)
Fenobam [N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea], a clinically validated non-benzodiazepine anxiolytic, has been shown to be a potent and non-competitive(More)
1. Several combinations of cysteine to serine mutations at positions 57, 93, 99 and 129 in the extracellular N-terminal domain of human metabotropic 5a (hmGlu5a) receptors were produced and expressed(More)
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