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The definition of context experienced an evolution in the research area of context-aware computing, but still suffers from either generality or in-completeness. Furthermore, many definitions are driven by the ease of implementation. This paper introduces two extensions to available context definitions that provide a natural understanding of this concept to(More)
PURPOSE Based on our first experiences with real-time elastography in the field of prostate diagnostics we evaluate its usefulness for biopsy guidance for prostate cancer detection. MATERIALS AND METHODS After imaging with conventional B-mode ultrasound in conjunction with real-time elastography 404 men underwent systematic sextant biopsy. RESULTS(More)
The Wnt/β-catenin signaling pathway plays crucial roles in early hindbrain formation, and its constitutive activity is associated with a subset of human medulloblastoma, a malignant childhood tumor of the posterior fossa. However, the precise function of Wnt/β-catenin signaling during cerebellar development is still elusive. We generated(More)
To utilize interactive multimedia applications in public and private environments for advertisement, entertainment and user guidance requires remote input capabilities. The use of mobile and handheld devices is a desirable option for implementation of user interaction with remote services from a distance. Another prominent option to operate a remote(More)
Currently, much research aims at coping with the shortcomings in multimedia consumption that may exist in a user's current context, e.g., due to the absence of appropriate devices at many locations, a lack of capabilities of mobile devices, restricted access to content, or non-personalized user interfaces. Recently, solutions to specific problems have been(More)
OBJECTIVE To assess the use of real-time elastography (RTE) for detecting prostate cancer in patients scheduled for radical prostatectomy (RP), as most solid tumours differ in their consistency from the deriving tissue, and RTE might offer a new tool for cancer detection. PATIENTS AND METHODS We examined 15 patients (mean age 56 years, sd 6.2, range(More)
To search for proteins interacting with the glucocorticoid receptor, we adapted Aronheim's reverse RAS recruitment system relying on the Saccharomyces cerevisiae mutant cdc25-2, which has a temperature-dependent defect in its RAS signaling pathway driving proliferation. The full-length human glucocorticoid receptor (NR3C1, isoform-alpha) was attached to the(More)
In the field of mobile health monitoring the current most important user groups are those aged 50+. In our project senSAVE r we developed a user interface for monitoring vital personal parameters that is specifically adapted to the needs of this group. The group is said to show less perception and control capability and has less experience in the use of(More)
Supporting the individual user in his working, learning, or information access is one of the main goals of user modeling. Personal or group user models make it possible to represent and use information about preferences, knowledge, abilities, emotional states, and many other characteristics of a user to adapt the user experience and support. Nowadays, the(More)