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In this report, we show that ionizing radiation (IR) at a clinically relevant dose (4 Gy) causes apoptosis in macrovascular and microvascular human endothelial cells. Treatment of irradiated cells with a low dose of bacterial endotoxin (LPS), similar to the levels observed in serum during endotoxemia, enhanced the rate of apoptosis, although LPS alone was(More)
Previous work from our group has contributed to demonstrate the role of conditioning related release of proinflammatory cytokines in induction of acute graft-versus-host disease (GVHD) following allogeneic bone marrow transplantation (BMT). In the present report we show that ionizing radiation (IR) in a clinical relevant dose upregulates intercellular(More)
This paper describes the implementation of an ANSYS Parametric Design Language (APDL) macro called CAMACO for the computation of capacitance matrixes of arbitrarily shaped 3D objects in arbitrarily distributed dielectrics via the conservation of field energies. APDL as the interface language of the general purpose FEM system ANSYS-Multiphysics™ provides an(More)
Unimolecular decay of sample ions imposes a limit on the usable laser fluence in matrix-assisted laser desorption/ionization (MALDI) ion sources. Traditionally, some modest degree of collisional sample ion cooling has been achieved by connecting MALDI ion sources directly to gas-filled radio frequency (RF) multipoles. It was also discovered in the early(More)
The study of microsystems containing photonic crystals (PC) and meta-materials are rapidly growing fields of research. Finite-Difference Time-Domain (FDTD) full wave electromagnetic solvers are now increasingly used to investigate and design such systems. However, in order to simulate the electromagnetic response of such complex systems containing a large(More)
A fundamental problem of all FEM capacitance computations in MEMS and ULSI is to determine proper mesh size for the elements representing the considered model. In particular, optimal mesh size selection is crucial for large 3D models to limit the required computational effort. However, automatic mesh refining algorithms are not applicable and/or desirable(More)
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