Andreas Freitag

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BACKGROUND Critically ill patients with renal insufficiency are predisposed to both deep vein thrombosis (DVT) and bleeding. The objective of the present study was to evaluate the prevalence, incidence and predictors of DVT and the incidence of bleeding in intensive care unit (ICU) patients with estimated creatinine clearance <30 ml/min. METHODS In a(More)
BACKGROUND The decision to have lung transplantation as treatment for end-stage lung disease from cystic fibrosis (CF) has benefits and serious risks. Although patient decision aids are effective interventions for helping patients reach a quality decision, little is known about implementing them in clinical practice. Our study evaluated a sustainable(More)
BACKGROUND Many patients with cystic fibrosis develop persistent airway infection/colonization with Aspergillus fumigatus, however the impact of A. fumigatus on clinical outcomes remains unclear. The objective of this study was to determine whether treatment directed against Aspergillus fumigatus improves pulmonary function and clinical outcomes in patients(More)
BACKGROUND Cystic fibrosis is the most common fatal autosomal recessive genetic disease in the Caucasian population. Osteoporosis is increasingly being recognised as an important complication in people with cystic fibrosis. METHODS A descriptive study of adult cystic fibrosis patients receiving care at a Canadian tertiary care hospital was conducted to(More)
BACKGROUND Previous studies have suggested that prediction models for mortality should be adjusted for additional risk factors beyond the Acute Physiology and Chronic Health Evaluation (APACHE) score. Our objective was to identify risk factors independent of APACHE II score and construct a prediction model to improve the predictive accuracy for hospital and(More)
Erratum In the original publication of this article [1], one of the co-authors' names was listed incorrectly. 'Lauzier Francois' should have been listed as 'Francois Lauzier'. References 1. Li G, et al. Risk factors for mortality in patients admitted to intensive care units with pneumonia. permits unrestricted use, distribution, and reproduction in any(More)
BACKGROUND Despite the high mortality in patients with pneumonia admitted to an ICU, data on risk factors for death remain limited. METHODS In this secondary analysis of PROTECT (Prophylaxis for Thromboembolism in Critical Care Trial), we focused on the patients admitted to ICU with a primary diagnosis of pneumonia. The primary outcome for this study was(More)
—Mergers and acquisitions (M&A) have become frequent events in today's economy. They are complex strategic transformation projects affecting both-business and information technology (IT). Still, empirical studies reveal high failure rates regarding the achievement of previously defined objectives. Taking into account the role and importance of IT in modern(More)
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