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Intravenous cyclosporine has proven to be an alternative to emergency colectomy in steroid-refractory ulcerative colitis, whereas the experience with FK506 is limited. In this report we compare intravenous to oral FK506 treatment in 38 patients with refractory ulcerative (n = 33) or indeterminate (n = 5) colitis. FK506 was started intravenously in the first(More)
OBJECTIVE The diagnostic significance of increased splanchnic blood flow in Crohn's disease is unclear. This prospective study was therefore undertaken to define the role of Doppler sonography in the assessment of disease activity and in the prediction of early relapse. METHODS Splanchnic flowmetry was performed in 59 patients with Crohn's disease and 20(More)
OBJECTIVE Mesenteric blood flow measurement has been found to predict relapse after steroid-induced remission in patients with Crohn's disease (CD) and ulcerative colitis (UC). Therefore, we assessed prospectively the possible relationship between changes in mesenteric blood flow and prognosis in chronically active patients with need of immunosuppressive(More)
Summary form only given. We propose architecture and a general optimization framework for dynamic, distributed real-time systems. Interesting features of this model include the consideration of adaptive applications and utility functions. We extend by formalizing the corresponding multicriterial optimization problem. As the most difficult part of this(More)
Octreotide is effective during 48 h in the treatment of acute variceal bleeding, probably by reducing variceal blood flow and pressure. Its basal and postprandial effects on splanchnic and systemic hemodynamics, and hormonal changes over this time interval have not yet been studied. Twenty-four patients with cirrhosis and portal hypertension were randomized(More)
BACKGROUND/AIMS Diminished postprandial portal hyperemia has been demonstrated by echo-Doppler flowmetry in patients with liver cirrhosis, but its diagnostic role is unclear. This prospective study was therefore undertaken in patients with varying severity of portal hypertension and degree of liver cirrhosis. METHODS Portal flowmetry was performed in 66(More)
This paper presents a novel concept for resource management in cluster-based image retrieval systems. First, the paper describes image retrieval using static and dynamic feature extraction. The complexity of dynamic feature extraction requires the utilization of powerful parallel architec-tures and in order to provide the user with reasonable response(More)
The following article contains a short review on gastrointestinal problems of the elderly. The diseases of the esophagus occurring in the elderly are not much different from those in younger patients. Clinically relevant in the stomach are above all bleeding ulcerations and the gastric carcinoma occurring more frequently in advanced age. The pyogenic liver(More)
BACKGROUND Octreotide is a potent splanchnic hypotensive somatostatin analogue effective in the treatment of acute variceal bleeding. AIM To study the effects of octreotide on basal and postprandial splanchnic and systemic haemodynamics, and hormonal changes in humans. METHODS Twenty-four healthy volunteers were randomized to receive a liquid meal and(More)