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The previous case study (Chapter 5) demonstrated that the analysis of the digital footprints people leave behind them seems to lead to an improved understanding of different aspects of mobility, travel and tourism. For instance, information about who populates different parts of the city at different times can lead to the provision of customized services,(More)
This paper illustrates how aggregated mobile phone network activity logs provide anonymous information that reveals valuable insight into the presence of tourists visiting a city. Technologies supporting pervasive services like cellular networks have the potential to generate vast quantities of detailed subscriber data, raising important privacy concerns.(More)
Acute intoxication and chronic therapy with the alcohol consumption deterrent dithiocarbamate disulfiram have been associated with several neurological complications perhaps involving the impairment of neurotransmitter pathways. In this study we have tested the hypothesis that dopaminergic malfunction is a critical component in disulfiram-evoked(More)
The [3H]Tyramine (TY) binding site is proposed as a high affinity marker of the membrane carrier for dopamine (DA) in synaptic vesicles from DA-rich brain regions. Under precise assay conditions, there is neither a consistent association of TY with the neuronal, cocaine-sensitive DA transporter, nor with mitochondrial or microsomal targets. TY-labeled sites(More)
Over the past decade there has been an explosion in the deployment of pervasive systems like cell phone networks and content aggregators on the Internet that produce massive amounts of data as by-products of their interaction with users. This data is related to the actions and opinions of people and thereby to the overall dynamics of cities, how they(More)
A holistic framework for the study of urban traces and the profiling of urban processes and dynamics This paper might be a pre-copy-editing or a post-print author-produced .pdf of an article accepted for publication. For the definitive publisher-authenticated version, please refer directly to publishing house's archive system. Abstract—Pervasive systems(More)
1. In the present study we provide evidence for a saturable, Mg2+/ATP- and temperature-dependent, tetrabenazine-, dopamine-, and amphetamine-sensitive uptake of 1-methyl-4-phenylpyridinium ion (MPP+) in synaptic vesicles from mouse striatum. 2. Similarity in the properties of the vesicular uptake suggests that in the striatum dopamine and MPP+ share the(More)
Intoxication with the alcohol-aversive drug disulfiram (Antabuse) and related dithiocarbamates may provoke neuropathies and, in some cases, damage the basal ganglia. Rats received a single administration of disulfiram (7 and 500 mg kg-1 i.p.) and equimolar doses (4 and 290 mg kg-1 i.p.) of its metabolite diethyldithiocarbamate (DDC), roughly corresponding(More)
Oral administration of the antithyroid drug methimazole (50 mg/kg per day) to rats during the last six days of pregnancy, and subsequent daily s.c. injection of methimazole (20-30 mg/kg) to their pups from birth to postnatal day 30 provoked hormonal and somatic alterations resembling (with all caution to any association between rodent and human data) those(More)
—In this paper, we outline an algorithm for the automatic segmentation of sparse data in order to detect possible terrain-deformation phenomena. Segmentation is accomplished through a graph cut technique. In the graph structure, for each edge, we derive a unique energy by combining multiple independent energies tailored toward accurately locating the(More)