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Adipogenesis plays a critical role in energy metabolism and is a contributing factor to the obesity epidemic. This study examined the proteome of primary cultures of human adipose-derived adult stem (ADAS) cells as an in vitro model of adipogenesis. Protein lysates obtained from four individual donors were compared before and after adipocyte differentiation(More)
Single motor unit activity was recorded from human lower lip muscles while subjects maintained a firing rate of 20 ips using audio and visual feedback. Each motor unit was classified as belonging to one of three muscles, orbicularis oris inferior (OOI), mentalis (MENT), or depressor labii inferior (DLI). Reflex responses were elicited in single motor units(More)
1. The ability of eleven normal subjects to match the position of the proximal interphalangeal joints was tested. The right index finger (target finger) was moved to a given position and the subject was required to match this with the left index finger (matching finger). 2. Digital nerve block of the matching finger resulted in substantial impairment in(More)
The researchers explored the effectiveness of Visual Phonics as a reading instructional tool when used in conjunction with a modified version of the Fountas and Pinnell Kindergarten Phonics Curriculum (Fountas & Pinnell, 2002) with a preschool student who was deaf. The study participant was a 4-year-old deaf child who had a cochlear implant. The goal of the(More)
Injections of rhodamine-B into the dorsal raphe nucleus (DRN) and Fluoro-Gold into the lateral geniculate nucleus (LGN) revealed double-labeled retinal ganglion cells (DL RGCs) projecting to both nuclei. The soma-size distribution of DL RGCs was compared with three other distributions: DRN-projecting RGCs, LGN-projecting RGCs, and a large sample of RGCs(More)
Position matching at the proximal interphalangeal joint of the index finger in human subjects was tested by passive displacement of the right (target) finger and active matching of the left index finger. In 5 subjects it was found that position matching was grossly impaired after digital nerve block of the matching finger. Typically, subjects hyperextended(More)
INTRODUCTION Radioprotective agents are of interest for application in radiotherapy for cancer and in public health medicine in the context of accidental radiation exposure. Methylproamine is the lead compound of a class of radioprotectors which act as DNA binding anti-oxidants, enabling the repair of transient radiation-induced oxidative DNA lesions. This(More)
A rabbit model for fentanyl-induced chest wall rigidity and the effect of apomorphine was evaluated. Eleven New Zealand adult rabbits were anesthetized and mechanically ventilated. An esophageal balloon catheter was used to estimate pleural pressure (P(pl)). Chest wall compliance (C(cw)) at baseline was calculated during pentobarbital anesthesia. A loading(More)
The calcitonin gene related peptide (CGRP) pathway is important in many processes including several in the central and peripheral nervous systems. CGRP is present in motor neurons and in sensory tracts, with its expression likely regulated by its use. This is supported by the fact that axotomy results in increased CGRP production in the nerve cell body. The(More)
1. Proprioceptive acuity was tested at the proximal interphalangeal joint of the index finger of normal subjects. 2. Examination of the ability of the subjects to match finger positions (position matching procedure) revealed that digital nerve block (DNB) of the finger resulted in characteristic alignment errors at the extremes in all subjects. 3. When one(More)
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