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  • Andrea R Mazzocchi, Mahesh Devarasetty, Richard Huntwork, Shay Soker, Aleksander Skardal
  • Materials Science, Medicine
  • Biofabrication
  • 2018 (First Publication: 30 October 2018)
  • Current 3D printing of tissue is restricted by the use of biomaterials that do not recapitulate the native properties of the extracellular matrix (ECM). These restrictions have thus far preventedContinue Reading
  • Andrea R Mazzocchi, Shiny Amala Priya Rajan, Konstantinos Ioannis Votanopoulos, Adam R. Hall, Aleksander Skardal
  • Medicine
  • Scientific Reports
  • 2018 (First Publication: 1 December 2018)
  • Variability in patient response to anti-cancer drugs is currently addressed by relating genetic mutations to chemotherapy through precision medicine. However, practical benefits of precision medicineContinue Reading
  • Konstantinos Ioannis Votanopoulos, Andrea R Mazzocchi, +4 authors Aleksander Skardal
  • Medicine
  • Annals of Surgical Oncology
  • 2018
  • IntroductionWe have hypothesized that biofabrication of appendiceal tumor organoids allows for a more personalized clinical approach and facilitates research in a rare disease.MethodsAppendicealContinue Reading
  • Robert N. Carter, Stephanie M Casillo, Andrea R Mazzocchi, Jon-Paul S. DesOrmeaux, James A. Roussie, Thomas R Gaborski
  • Materials Science, Medicine
  • Biofabrication
  • 2017 (First Publication: 14 February 2017)
  • Typical in vitro barrier and co-culture models rely upon thick semi-permeable polymeric membranes that physically separate two compartments. Polymeric track-etched membranes, while permeable to smallContinue Reading
  • Konstantinos Ioannis Votanopoulos, Steven D. Forsythe, +6 authors Aleksander Skardal
  • Medicine
  • Annals of Surgical Oncology
  • 2019 (First Publication: 19 December 2019)
  • We hypothesized that engineering a combined lymph node/melanoma organoid from the same patient would allow tumor, stroma, and immune system to remain viable for personalized immunotherapy screening.Continue Reading