Andrea M. LeFevre

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CONTEXT Poor adherence to treatment remains a major obstacle to efficient tuberculosis (TB) control in developing countries. Innovative strategies to improve access and adherence to treatment are needed. OBJECTIVES To assess the effectiveness of a contextualized intervention strategy aimed at improving patients' adherence to treatment and to evaluate its(More)
BACKGROUND Detection and treatment of latent TB infection (LTBI) in HIV infected individuals is strongly recommended to decrease morbidity and mortality in countries with high levels of HIV. OBJECTIVE To assess the validity of a newly developed in-house ELISPOT interferon-gamma release assay (IGRA) for the detection of LTBI amongst HIV infected(More)
1 Laboratoire de Bactériologie – Virologie, Hôpital Aristide Le Dantec, Dakar, Senegal, 2 Institut de Recherche pour le Développement, Programme Tuberculose, Dakar, Senegal, 3 Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom, 4 Clinique des Maladies Infectieuses, Hopital Fann, Dakar,(More)
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