Andrea Lazzeri

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The intratumoral injection of cytokines, in particular IL2, has shown promise for cutaneous melanoma patients with unresectable disease or continuous recurrence despite surgery. We recently reported that the intralesional injection of L19-IL2, an immunocytokine combining IL2 and the human monoclonal antibody fragment L19, resulted in efficient regional(More)
Gelatin, a natural macromolecular proteic material from renewable resources, is widely used in many industrial applications. In this study gelatin scraps, deriving from pharmaceutical capsule productions, were turned into films by casting water solutions or suspensions producing flexible and consistent films. Gelatin was blended with poly(vinyl alcohol), a(More)
There is increasing research towards the substitution of petrochemicals by sustainable components. Biopolymers such as proteins, polysaccharides, and lipids derive from a variety of crop sources and most promisingly from waste streams generated during their processing by the agro food industry. Among those, proteins of different types such as whey, casein,(More)
The agronomic characteristics of Ramie and Spanish Broom were investigated for seven years in the pedoclimatic conditions of Central Italy. The chemical, physical and mechanical properties of these fibres were also examined in order to evaluate the feasibility to use them in composite materials. Results demonstrate that Ramie grown in the temperate(More)
We experimentally investigate the benefits of a new optical pulse coding technique for long-range, meter and submeter scale Raman-based distributed temperature sensing on standard single-mode optical fibers. The proposed scheme combines a low-repetition-rate quasi-periodic pulse coding technique with the use of standard high-power fiber lasers operating at(More)
In this paper we present a high-performance configurable multi-channel counter, suitable for many scientific applications. The counter array features 64 input channels, is able to acquire incoming events with a pulse rate up to 45 MHz, and provides an integration window (time resolution) down to 24 mus with a 32 b counting depth. Moreover, the time(More)
Presented is a novel approach for enhancing the signal-to-noise ratio (SNR) of optical fibre distributed temperature sensors. The proposed method is based on cyclic codes and it can be implemented by highpower lasers, which are required for long-range applications but are unsuitable for conventional coding techniques. The expected performance improvement,(More)
A series of experimental precipitated calcium carbonates (PCCs) coated with commercial stearic acid (stearin), with the coating amount of stearin added to the PCC particles ranging from 3 to 13.5 wt %, were prepared in aqueous medium and characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and differential(More)
Multilayer plastic films provide a range of properties, which cannot be obtained from monolayer films but, at present, their recyclability is an open issue and should be improved. Research to date has shown the possibility of using whey protein as a layer material with the property of acting as an excellent barrier against oxygen and moisture, replacing(More)