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We have shown that among pathogens, populations may self-organize into strains with non-overlapping repertoires of antigenic variants as a consequence of strong immune selection operating on polymorphic antigens. Recently, we have also demonstrated that over a wide range of intermediate levels of immune selection, pathogens may still be structured into… (More)
Citrobacter diversus is closely related to brain abscess in newborn infants. We describe a case of brain abscess by this bacteria in a newborn infant and his clinical and cranial computed tomographic evaluation until the fourth month of life and discuss therapeutic management of this patient.
The LISP-MN protocol is an extension of the Locator/ID Separation Protocol (LISP) that support end-host IP mobility and that, to operate, requires updating the software of the mobile terminal. However in several scenarios this is a major roadblock to effectively deploy mobility. On the one hand the operator must support the implementation over a wide range… (More)
We review how constraints on the mating probability of female worms by segregation within individual host guts form a critical element in the parasite population structure of nematodes. We consider the effects of these constraints on the population genetics of nematodes under various assumptions regarding worm competition as reflected in the relationship… (More)
The restoration of the hip centre of rotation in an anatomical position is considered to be relevant for total hip prosthesis survival. When the cup is implanted with a high centre of rotation, the lever arm of the abductor muscles is decreased, causing higher joint-reaction forces. Modular stems with varying lengths and geometries can be used to balance… (More)
Approaching disease elimination, it is crucial to be able to assess progress towards key objectives using quantitative tools. For Gambian human African trypanosomiasis (HAT), the ultimate goal is to stop transmission by 2030, while intermediary targets include elimination as a public health problem - defined as <1 new case per 10,000 inhabitants in 90% of… (More)