Andrea De Giusti

Learn More
Atypical fractures of the femur below the lesser trochanter have been reported in patients treated with bisphosphonates. We performed a systematic literature search of case/case series studies to better define the clinical presentation and to identify characteristics that may predispose patients to such fractures. We considered only women treated with a(More)
Atypical subtrochanteric/femoral shaft (ST/FS) fractures are increasingly reported in patients on long-term treatment with bisphosphonates (BPs). We estimated the frequency of atypical fractures and their association to BP use in patients aged ≥ 50 years consecutively admitted to a single center with a new femoral fracture. All individual radiographs were(More)
In order to assess the liver protective activity and the antioxidant properties of a new silybin complex (IdB1016), we carried out a short-term pilot study on 20 patients with chronic active hepatitis (CAH), randomly assigned to 240 mg of silybin b.i.d. (10 patients, 4 m/6 f, mean age: 50 years) or placebo (10 patients, 2 m/8 f, mean age: 55 years). Blood(More)
Dear Editor, In a recent issue of Osteoporosis International Sakuma et al. demonstrated a higher prevalence of hypovitaminosis D and secondary hyperparathyroidism (sHPTH) in elderly patients with hip fracture than in non-osteoporotic controls [1]. One of the conclusions of the authors was that serum 25hydroxyvitamin D (25-OHD) may be a useful index to(More)
Atypical fractures of the femur have been reported to occur in patients on long-term treatment with bisphosphonates; however, causality has not been proven, and it is not known whether similar fractures may occur in other long bones. We addressed this issue by examining the relationship between humeral shaft fractures and bisphosphonate use. We identified(More)
We consider the problem of compressing memoryless binary data with or without side information at the decoder. We review the parityand the syndrome-based approaches and discuss their theoretical limits, assuming that there exists a virtual binary symmetric channel between the source and the side information, and that the source is not necessarily uniformly(More)
AIM Physical therapy efficacy in the treatment of low back pain (LBP) has been widely debated and is far from achieving high levels of evidence. Hydroelectrophoresis (Hydrofor) is a novel method of driving drugs through the dermal tissue, which has been proposed for muscle pain treatment. Aim of this randomised placebo-controlled study was to ascertain the(More)