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Circulating monocytes in HIV-1-infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance.

• Malavika S. Giri, Michael Nebozyhn, +13 authors Luis J Montaner
• Journal of immunology
• 2009

Mechanisms that may allow circulating monocytes to persist as CD4 T cells diminish in HIV-1 infection have not been investigated. We have characterized steady-state gene expression signatures in… (More)

HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals.

• Andrea D Raymond, T C Campbell-Sims, +4 authors Michael D. Powell
• AIDS research and human retroviruses
• 2011

HIV-1 Nef has been demonstrated to be integral for viral persistence, infectivity, and the acceleration of disease pathogenesis (AIDS) in humans. Nef has also been detected in the plasma of… (More)

Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia.

• Andrea D Raymond, Bethsebah N Gekonge, +11 authors Luis J Montaner
• Journal of leukocyte biology
• 2010

Circulating monocytes exhibit an apoptotic resistance phenotype during HIV viremia in association with increased MT expression. MTs are known to play an important role in zinc metabolism and immune… (More)

Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study.

• Bethsebah N Gekonge, Andrea D Raymond, +5 authors Luis J Montaner
• Journal of leukocyte biology
• 2012

We have previously described an antiapoptotic steady-state gene expression profile in circulating human monocytes from asymptomatic viremic HIV(+) donors, but the mechanism associated with this… (More)

Microglia-derived HIV Nef+ exosome impairment of the blood–brain barrier is treatable by nanomedicine-based delivery of Nef peptides

• Andrea D Raymond, Paulo H. Diaz, +9 authors Madhavan P. N. Nair
• Journal of NeuroVirology
• 2015

The negative factor (Nef) of human immunodeficiency virus (HIV) is an accessory protein that is thought to be integral to HIV-associated immune- and neuroimmune pathogenesis. Here, we show that… (More)

Herpesvirus saimiri terminal membrane proteins modulate HIV-1 replication by altering Nef and Tat functions.

• Andrea D Raymond, Muneer G. Hasham, Alexander Y Tsygankov, Earl E. Henderson
• Current HIV research
• 2007

Herpesvirus saimiri (HVS)-transformed human T cells expressing terminal membrane proteins (TMPs) tyrosine kinase interacting protein (Tip) and saimiri transformation associated protein strain C… (More)

Herpesvirus saimiri-encoded proteins Tip and StpC modulate human immunodeficiency virus type 1 replication in T-cell lines and lymphocytes independently of viral tropism.

• Andrea D Raymond, Muneer G. Hasham, Alexander Y Tsygankov, Earl E. Henderson
• Virology
• 2004

Herpesvirus saimiri (HVS)-transformed T-lymphocytes are permissive for both X4 and R5 strains of human immunodeficiency virus type 1 (HIV-1). HVS-encoded proteins tyrosine-kinase interacting protein… (More)

H. saimiri tyrosine-kinase interacting protein inhibits Tat function: a prototypic strategy for restricting HIV-1-induced cytopathic effects in immune cells.

• Andrea D Raymond, Muneer G. Hasham, Alexander Y Tsygankov, Earl E. Henderson
• Virology
• 2006

Herpesvirus saimiri (HVS)-transformed human T cells become permissive for X4 and R5 strains of human immunodeficiency virus type 1 (HIV-1), evidence that HVS-encoded proteins associated with T cell… (More)

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