Andrea Centrone

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Multifunctional nanomaterials have the potential to integrate the clinical paradigms of imaging and therapy to enable real-time visualization of therapeutic biodistributions in patients. For cancer therapy, nanomaterials with capacities to be remotely detected and triggered for therapy could also close the loop between tumor detection and treatment. In this(More)
The pharmaceutical industry has great interest in organic molecular nanosized crystals because their enhanced solubility and dissolution rate can potentially enhance drug bioavailability. In this work, patterned engineered surfaces were used to crystallize glycine with a lateral dimension below 200 nm in a confined volume while controlling supersaturation.(More)
The ability of one structural type to perform multiple medical diagnostic or therapeutic functions is often cited as an advantageous characteristic of nanomaterials that cannot be achieved with organic small molecules. [1–3] Although there are now many examples of nanosystems that integrate multiple functions into a single structure, the designs can reduce(More)
Photothermal induced resonance (PTIR) has recently attracted great interest for enabling chemical identification and imaging with nanoscale resolution. In this work, electron beam nanopatterned polymer samples are fabricated directly on 3D zinc selenide prisms and used to experimentally evaluate the PTIR lateral resolution, sensitivity and linearity. It is(More)
We report a strategy for realizing tunable electrical conductivity in metal-organic frameworks (MOFs) in which the nanopores are infiltrated with redox-active, conjugated guest molecules. This approach is demonstrated using thin-film devices of the MOF Cu3(BTC)2 (also known as HKUST-1; BTC, benzene-1,3,5-tricarboxylic acid) infiltrated with the molecule(More)
Polymer substrates have been functionalized with a MOF material (MIL-47) synthesized directly on polyacrylonitrile using in situ microwave irradiation. The growth of MIL-47 on these substrates was studied as a function of microwave irradiation time using scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and X-ray(More)
Dr. R. Dong, Dr. Y. Fang, Z. Xiao, Dr. Q. Dong, Dr. Y. Yuan, Prof. X. C. Zeng, Prof. J. Huang Department of Mechanical and Materials Engineering University of Nebraska-Lincoln Lincoln , NE 68588 , USA E-mail: Dr. J. Chae, Dr. A. Centrone Center for Nanoscale Science and Technology National Institute of Standards and Technology 100 Bureau(More)
The tunable properties of stimulus-responsive materials attract great interest in a variety of technological applications. Photonic gels are a new class of these materials, which can be tuned to reflect different wavelengths of light. Controlling this reflected color via temperature-induced changes of self-assembled photonic materials is important for their(More)
Self-assembled monolayer-protected nanoparticles are promising candidates for applications, such as sensing and drug delivery, in which the molecular ligands' interactions with the surrounding environment play a crucial role. We recently showed that, when gold nanoparticles are coated with a binary mixture of immiscible ligands, ordered ribbon-like domains(More)