Andrea Cawein

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A double blind, randomized, controlled trial compared the safety and immunogenicity of an acellular pertussis vaccine formulated at Lederle using the Takeda acellular pertussis component combined with Lederle diphtheria and tetanus toxoids vaccines (APDT), with the commercially available Japanese Takeda vaccine (APDT-T/J) as a three-dose series to 2-, 4-,(More)
A transformation assay system using two clonal strains of adult rat liver epithelial cells is described. The carcinogens N-methyl-N'-nitro-N-nitrosoguanidine, methylmethanesulfonate, N-2-fluorenylacetamide, aflatoxin B1, benzo(a)pyrene, dimethylnitrosamine, nitrosopyrrolidine, and dimethyl-4-aminoazobenzene induced anchorage independency in one or both(More)
Despite the success of vaccines in reducing the morbidity and mortality associated with infectious diseases, many infectious diseases, both newly emerging and well known, lack vaccines. The global capability for beginning-to-end vaccine development has become limited, primarily owing to a scarcity of human capital necessary to guide the development of novel(More)
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