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  • Federica Mastroiacovo, Carla L Busceti, +6 authors Ferdinando Nicoletti
  • Medicine
  • Journal of cerebral blood flow and metabolism…
  • 2009 (First Publication: 1 February 2009)
  • Inhibition of the canonical Wnt pathway has been implicated in the pathophysiology of neuronal death. Here, we report that the secreted Wnt antagonist, Dickkopf-1 (Dkk-1) is rapidly induced inContinue Reading
  • Luisa Iacovelli, Valeria Bruno, +6 authors Ferdinando Nicoletti
  • Biology, Medicine
  • Journal of neurochemistry
  • 2002 (First Publication: 3 July 2002)
  • We used cultured cerebellar granule cells to examine whether native group-III metabotropic glutamate (mGlu) receptors are coupled to the mitogen-activated protein kinase (MAPK) andContinue Reading
  • Carla Scali, Filippo Caraci, Marco Gianfriddo, Enrica Diodato, Andrea Caricasole
  • Medicine, Biology
  • Neurobiology of Disease
  • 2006 (First Publication: 1 November 2006)
  • Expression of the Wnt antagonist Dickkopf-1 (DKK1) is induced during neurodegenerative processes associated with Alzheimer's Disease and brain ischemia. However, little is known about DKK1-mediatedContinue Reading
  • Irene Cappuccio, Agata Calderone, +12 authors Andrea Caricasole
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 2005 (First Publication: 9 March 2005)
  • Expression of Dickkopf-1 (Dkk-1), a secreted protein that negatively modulates the Wnt pathway, was induced in the hippocampus of gerbils and rats subjected to transient global cerebral ischemia asContinue Reading
  • Agata Copani, Daniela Melchiorri, +8 authors Ferdinando Nicoletti
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 2002 (First Publication: 15 May 2002)
  • We have shown that cortical neurons challenged with toxic concentrations of beta-amyloid peptide (betaAP) enter the S phase of the cell cycle before apoptotic death. Searching for a signalingContinue Reading