Andrea Buda

Learn More
Internet of Things (IoT) is intended to provide a network where information flows could easily be set up between any kinds of products, devices, users and information systems in general. This vision is getting closer to become real due to the continuous development of new information system concepts and technologies. Nonetheless, this new reality requires(More)
Hepatocellular carcinoma (HCC) and liver cirrhosis (LC) are not well-established vinyl chloride monomer (VCM)-induced diseases. Our aim was to appraise the role of VCM, alcohol intake, and viral hepatitis infection, and their interactions, in the etiology of HCC and LC. Thirteen cases of HCC and 40 cases of LC were separately compared with 139 referents(More)
OBJECTIVES A growing body of evidence indicates that patients with sessile serrated adenoma/polyp (SSA/P) and traditional serrated adenoma (TSA) are at risk for subsequent malignancy. Despite increasing knowledge on histological categorization of serrated polyps (SPs) data are lacking on the actual prevalence and the association of each SP subtype with(More)
Abnormal levels of microRNA (miR)-155, which regulate inflammation and immune responses, have been demonstrated in the colonic mucosa of patients with inflammatory bowel diseases (IBD), although its role in disease pathophysiology is unknown. We investigated the role of miR-155 in the acquisition and maintenance of an activated phenotype by intestinal(More)
Nowadays, organizations make a point of protecting the confidentiality of their data and assets using firewalls, proxies and NATs, which goes against providing a high level of data usability and interoper-ability between distinct information systems, or " Things " in the so-called Internet of Things. Such security procedures often prevent two-way(More)
Recent advancement in web technology enabled the development of new Business-to-Business (B2B) infrastructures, e.g. based on the concept of Service Oriented Architecture (SOA). These infrastructures enable seamless information exchange among different stakeholders and complex business procedures. However, there is still a lack of sufficiently generic and(More)
Inflammatory bowel diseases are chronic gastrointestinal pathologies causing great discomfort in both children and adults. The pathogenesis of inflammatory bowel diseases is not yet fully understood and their diagnosis and treatment are often challenging. Nanoparticle-based strategies have been tested in local drug delivery to the inflamed colon. Here, we(More)
In patients with ulcerative colitis (UC) the cumulative risk of colon cancer is lower than the actual rate of dysplasia suggesting an efficient immune surveillance mechanism. Since the co-stimulatory molecule CD80 is overexpressed in dysplastic colonic mucosa of UC patients and T-cell activation entails effective costimulation, we aimed to evaluate the(More)