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The US National Institutes of Health has developed a repository of clinical research data drawn in part from electronic health records. A new de-identified data query tool under development has been developed to support re-use of these data. We used a collection of 30 human-mediated user queries to determine whether features of the tool will be sufficient(More)
The US National Institutes of Health (NIH) has developed the Biomedical Translational Research Information System (BTRIS) to support researchers' access to translational and clinical data. BTRIS includes a data repository, a set of programs for loading data from NIH electronic health records and research data management systems, an ontology for coding the(More)
Preclinical changes that precede the onset of symptoms and eventual diagnosis of Alzheimer's disease (AD) are a target for potential preventive interventions. A large body of evidence suggests that inflammation is closely associated with AD pathogenesis and may be a promising target pathway for such interventions. However, little is known about the(More)
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