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Large platelet aggregates in endoscopic ultrasound‐guided fine‐needle aspiration of the pancreas and peripancreatic region: A clue for the diagnosis of intrapancreatic or accessory spleen
TLDR
A review of 10 consecutive cases of EUS‐FNA‐sampled benign intraabdominal lymph nodes showed that the presence of large platelet aggregates, three‐dimensional aggregates of lymphoid cells and of bland slender spindle cells and the absence of follicular germinal cell components are useful in differentiating IPIASs from reactive lymph nodes.
Umbilical Granuloma in a 2-Month-Old Patient: Histopathology of a Common Clinical Entity.
TLDR
The authors present the histology of this clinical finding in a 2-month-old infant, as it is important for the pathologist to be aware of this benign entity and distinguish it from other umbilical anomalies that may be of greater clinical significance.
Expression of CK7, Cam 5.2 and Ber‐Ep4 in cutaneous squamous cell carcinoma
Cytokeratin 7 (CK7) and Cam 5.2 are often used to differentiate extramammary Paget's disease (EPD) from squamous cell carcinoma (SCC) in situ because they are generally considered to be expressed in
Prevention and delay in progression of human pancreatic cancer by stable overexpression of the opioid growth factor receptor.
TLDR
Data support OGFr gene function as a regulator of cell proliferation that impacts on tumorigenic expression, and suggest that molecular and pharmacological manipulation of OGFr may prevent or delay human pancreatic cancer.
Occult Primary Medullary Thyroid Carcinoma Presenting with Pituitary and Parotid Metastases: Case Report and Review of the Literature
TLDR
A rare case of an occult MTC is reported, which presented with clinical symptoms associated with synchronous metastases diagnosis and may be amenable to therapy with the recently available tyrosine kinase inhibitors.
Cytologic features of pancreatic adenocarcinoma with “vacuolated cell pattern.” report of a case diagnosed by endoscopic ultrasound‐guided fine‐needle aspiration
TLDR
The endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) cytologic features of a case of pancreatic adenocarcinoma with “vacuolated cell pattern” occurring in a 60‐year‐old man allowing its differentiation from primary and metastatic signet‐ring cell carcinomas are reported.
“Cannonballs” and psammoma bodies: Unusual cytologic features of metastatic pulmonary small‐cell carcinoma in a pleural effusion
TLDR
Metastatic pulmonary small‐cell carcinoma should be considered in the differential diagnosis of serous effusions showing large three‐dimensional neoplastic cell aggregates and psammoma bodies to prevent a potential diagnostic pitfall.
Crystallizing immunoglobulin presenting as polychromatic crystalline keratopathy: An unusual clinical presentation of monoclonal gammopathy of undetermined significance (MGUS)
TLDR
This case is unusual because the patient had a low disease burden based on percentage of plasma cells and M-spike; however the M-protein was crystallizing within the plasma cell cytoplasm and in the patient’s cornea.
Osteoid in cellblock sections of ascitic fluid: A clue for the diagnosis of hepatoblastoma
TLDR
Close examination of the pink trabeculae led to their interpretation as osteoid, and immunohistochemical stains were performed to confirm the hypothesis that the sheets of cells present in the sample represented neoplastic fetal-type hepatoblastoma cells rather than mesothelial cells.
Butterfly‐shaped nuclei in cerebrospinal fluid relapse of acute promyelocytic leukemia
TLDR
A 63-year-old man presented to the hospital for evaluation for hematopoietic stem cell transplantation after being diagnosed with acute promyelocytic leukemia two years previously and despite further chemotherapy with arsenic trioxide, the patient had continued evidence of disease by molecular studies.