Andre Manitius

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Mapping the brain and its complex networked structure has been one of the most researched topics in the last decade and continues to be the path towards understanding brain diseases. In this paper we present a new approach to estimating the connectivity between neurons in a network model. We use systems identification techniques for nonlinear dynamic models(More)
— We propose a new method for fitting model parameters to the neural spike train obtained from an experimental neuron. Due to the uncertainty associated with measuring the accurate voltage in a noisy environment, it is essential to develop methods that rely solely on the interspike intervals (ISI). Existing techniques do not provide a smooth and continuous(More)
The increasing need of knowledge in the treatment of brain diseases has driven a huge interest in understanding the phenomenon of neural spiking. Researchers have successfully been able to create mathematical models which, with specific parameters, are able to reproduce the experimental neuronal responses. The spiking activity is characterized using spike(More)
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