Andrés Sánchez - Pernaute

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Despite the well-documented association between insulin resistance and cardiovascular disease, the key targets of insulin relevant to the development of cardiovascular disease are not known. Here, using non-biased profiling methods, we identify the enzyme flavin-containing monooxygenase 3 (Fmo3) to be a target of insulin. FMO3 produces trimethylamine(More)
Lymph node involvement in adenocarcinoma of the esophagogastric junction (EGJ) is similar to that of gastric cancer. The impact on survival of the number and site of lymph nodes involved in a subgroup of patients undergone surgery for adenocarcinoma of EGJ is reported. Sixty-four patients undergone transthoracic esophagectomy with two-field lymphadenectomy(More)
A chordoma is a rare, low-grade, primary malignant bone tumor of ectodermal origin derived from cellular remnants of the primitive notochord [1]. Through development, the notochord is lost in areas where it is engulfed by developing vertebral bodies [2]. Notochord remnants within the vertebral bodies may develop into chordomas which can develop anywhere(More)
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