Andrés Machado

Learn More
reports have been published over recent years about the paradoxical " arousing " effect of Zolpidem, a highly selective nonbenzodiazepine gamma aminobutyric acid (GABA) agonist acting on the [omega]-1 site of the GABA A receptor, in persistent vegetative state (PVS), in minimally conscious state (MCS) patients, ischemic stroke cases, after brain injury, and(More)
OBJECTIVE To study the Zolpidem arousing effect in persistent vegetative state (PVS) patients combining clinical evaluation, autonomic assessment by heart rate variability (HRV), and EEG records. METHODS We studied a group of 8 PVS patients and other 8 healthy control subjects, matched by age and gender. The patients and controls received drug or placebo(More)
Heart rate variability (HRV) is often analysed using short-term studies. Our objective was to compare two of them in a group of diabetic patients (reduced HRV) and in a control group. From the same 10 min surface electrocardiogram (ECG) two recordings were obtained. In one of them the whole signal was acquired through an A/D converter (post-event method).(More)
  • 1