Andrés Eduardo Caicedo

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We show that the bounded proper forcing axiom BPFA implies that there is a well-ordering of P(ω1) which is Δ1 definable with parameter a subset of ω1. Our proof shows that if BPFA holds then any inner model of the universe of sets that correctly computes א2 and also satisfies BPFA must contain all subsets of ω1. We show as applications how to build minimal(More)
Mitochondrial activity is central to tissue homeostasis. Mitochondria dysfunction constitutes a hallmark of many genetic diseases and plays a key role in tumor progression. The essential role of mitochondria, added to their recently documented capacity to transfer from cell to cell, obviously contributes to their current interest. However, determining the(More)
OBJECTIVES To define how peroxisome proliferator-activated receptor (PPAR) β/δ expression level in mesenchymal stem cells (MSCs) could predict and direct both their immunosuppressive and therapeutic properties. PPARβ/δ interacts with factors such as nuclear factor-kappa B (NF-κB) and regulates the expression of molecules including vascular cell adhesion(More)
• At stage 0, M0 = M , U0 = U and κ0 = κ. • At stage α+1, if it is well-founded, we build Ult(Mα, Uα) and let Mα+1 be its transitive collapse, where the ultrapower is computed from the point of view of Mα. Let jα,α+1 : Mα → Mα+1 be the ultrapower embedding. Then set κα+1 = j(κα) and Uα+1 = j(Uα). • At limit stages λ, if it is well-founded, we define Mλ as(More)
The involvement of the coxsackie and adenovirus receptor (CAR), an adhesion molecule known to be the main determinant of adenovirus transduction of the cells, in cancer is currently under investigation. Recent reports suggest that CAR levels are elevated in breast cancer, and this may have an impact on its use as means of delivery for gene therapy. In this(More)
The aim of this work was to understand whether the nature of breast cancer cells could modify the nature of the dialog of mesenchymal stem cells (MSCs) with cancer cells. By treating MSCs with the conditioned medium of metastatic Estrogen-receptor (ER)-negative MDA-MB-231, or non-metastatic ER-positive MCF-7 breast cancer cells, we observed that a number of(More)
Stemness combines the ability of a cell to perpetuate its lineage, to give rise to differentiated cells, and to interact with its environment to maintain a balance between quiescence, proliferation, and regeneration. While adult Stem Cells display these properties when participating in tissue homeostasis, Cancer Stem Cells (CSCs) behave as their malignant(More)
Assume AD and that either V = L(P(R)), or V = L(T,R) for some set T ⊂ ORD. Let (X,≤) be a pre-partially ordered set. Then exactly one of the following cases holds: (1) X can be written as a well-ordered union of pre-chains, or (2) X admits a perfect set of pairwise ≤-incomparable elements, and the quotient partial order induced by (X,≤) embeds into (2,≤lex)(More)
Intercellular communications play a major role in tissue homeostasis and responses to external cues. Novel structures for this communication have recently been described. These tunneling nanotubes (TNTs) consist of thin-extended membrane protrusions that connect cells together. TNTs allow the cell-to-cell transfer of various cellular components, including(More)