André Pinheiro

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The extracellular matrix (ECM) of the trabecular meshwork (TM) is an important determinant of its functional properties. This study was performed to investigate whether overexpression of ECM components, laminin (LM) and collagen type IV (Col) by TM cells may play a role in the development of outflow resistance. To determine the effect of excess LM and Col(More)
PURPOSE To determine whether tight glycemic control prevents development of basement membrane (BM) thickening in retinal and glomerular capillaries of diabetic rats and whether the extent to which BM thickening develops is linked to fibronectin (FN) overexpression and the degree of hyperglycemia. METHODS Retinal and renal cortical tissues obtained from(More)
Mechanical maintenance of F-16 engines is carried out as a team effort involving 3 to 4 skilled engine technicians. This paper presents the development of a mechanical maintenance simulator for their training. This simulator aims to enable technician training to be enhanced with cooperation and context prior to the training phase with actual physical(More)
The reported study is the first part of an on-going work which objective is to produce a land cover classification of continental Portugal from multi-spectral and multi-temporal MODIS satellite images acquired at a 500 m nominal resolution. Our goal is to achieve an automatic pixel level classification using a Support Vector Machine (SVM) learning approach.(More)
1 INTRODUCTION..........................................................................................2 2 MODELS .......................................................................................................4 2.1 Common component dynamic linear models ........................................4 2.2 Special cases(More)
The paper shows a practical application of the use of Extended Kalman Filter (EKF) in determining the hydrodynamic derivatives of an Autonomous Underwater Vehicle for a (AUV). The work is worth the experimental results of the underwater vehicle "Pirajuba" developed by LVNT (Not Manned Vehicle Laboratory) of Polytechnic School from University of São(More)
Spatial Data mining is one of the challenging field in data mining. The explosive development of spatial data and common use of spatial databases highlight the need for the automated detection of spatial knowledge. Computing data mining algorithms such as clustering on massive spatial data sets is still not feasible nor efficient today. In this research(More)
Cardiovascular Disease (CVD) is the single largest killer in the world. Although, several CVD treatment guidelines have been developed to improve quality of care and reduce healthcare costs, for a number of reasons, adherence to these guidelines remains poor. Further, due to the extremely poor quality of data in medical patient records, most of today’s(More)
This paper aims at presenting the usefulness of combining satellite optical data from the visible and infrared wavelengths with longer wavelength radar data for land cover mapping in Portugal. This is a ground-breaking study in a geographical region that does not experience continuous intraannual dreadful atmospheric contamination that commonly justifies(More)
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