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  • Derrick J Rossi, David Bryder, Jun Seita, André Nussenzweig, Jan H. J. Hoeijmakers, Irving L. Weissman
  • Biology, Medicine
  • Nature
  • 2007 (First Publication: 1 June 2007)
  • A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminishedContinue Reading
  • Gunnar Schotta, Roopsha Sengupta, +12 authors Thomas Jenuwein
  • Biology, Medicine
  • Genes & development
  • 2008 (First Publication: 1 August 2008)
  • H4K20 methylation is a broad chromatin modification that has been linked with diverse epigenetic functions. Several enzymes target H4K20 methylation, consistent with distinct mono-, di-, andContinue Reading