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1983
2018
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- André M. Cantin, Susan Lynn North, Richard C. Hubbard, Ronald G. Crystal
- Journal of applied physiology
- 1987
The epithelial cells on the alveolar surface of the human lower respiratory tract are vulnerable to toxic oxidants derived from inhaled pollutants or inflammatory cells. Although these lung cells… (More)
- André M. Cantin, Richard C. Hubbard, Ronald G. Crystal
- The American review of respiratory disease
- 1989
Glutathione (L-gamma-glutamyl-L-cysteinyl-glycine, GSH), a sulfhydryl-containing tripeptide produced by most mammalian cells, is an efficient scavenger of toxic oxidants, including hydrogen peroxide,… (More)
- R. Buhl, Howard A. Jaffe, +5 authors Ronald G. Crystal
- The Lancet
- 1989
To find out whether systemic glutathione deficiency is associated with human immunodeficiency virus (HIV) infection, thus contributing to the immunodeficiency state, glutathione concentrations in… (More)
- André M. Cantin, Susan Lynn North, Gerald A. Fells, Richard C. Hubbard, Ronald G. Crystal
- The Journal of clinical investigation
- 1987
Lung inflammatory cells of patients with idiopathic pulmonary fibrosis (IPF) were evaluated for their ability to injure 51Cr-labeled AKD alveolar epithelial cells in the presence and absence of IPF… (More)
- André M. Cantin, John W. Hanrahan, +5 authors Peter Durie
- American journal of respiratory and critical care…
- 2006
RATIONALE
Cigarette smoke extract inhibits chloride secretion in human bronchial epithelial cells. Oxidants decrease gene expression, protein expression, and function of the cystic fibrosis… (More)
- André M. Cantin, Dominik Hartl, Michael W Konstan, James F Chmiel
- Journal of cystic fibrosis : official journal of…
- 2015
Lung disease is the major cause of morbidity and mortality in patients with cystic fibrosis (CF). Although CF lung disease is primarily an infectious disorder, the associated inflammation is both… (More)
- Gabriel Mitchell, David Lalonde Séguin, +5 authors François Malouin
- BMC Microbiology
- 2009
Staphylococcus aureus and Pseudomonas aeruginosa are often found together in the airways of cystic fibrosis (CF) patients. It was previously shown that the P. aeruginosa exoproduct… (More)
- Gabriel Mitchell, Gilles Grondin, Ginette Bilodeau, André M. Cantin, François Malouin
- Infection and immunity
- 2011
The infection of nonphagocytic host cells by Staphylococcus aureus and more particularly by small-colony variants (SCVs) may contribute to the persistence of this pathogen in the lungs of cystic… (More)
- Benoit Paquette, M Sheldon Bisson, +4 authors André M. Cantin
- The Journal of Steroid Biochemistry and Molecular…
- 2003
Breast cancer patients frequently develop metastases. This process requires the degradation of extracellular matrix proteins which act as a barrier to tumour cell passage. These proteins can be… (More)
- K Arsalane, Claire M Dubois, +4 authors André M. Cantin
- American journal of respiratory cell and…
- 1997
Glutathione (GSH) is an essential antioxidant tripeptide that protects mammalian cells against oxidants and xenobiotics. Patients with fibrotic lung disorders have very low levels of GSH in their… (More)