André M. Leblanc

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A technique is described for adding natural-looking hair to standard rendering algorithms. Using an explicit hair model in which each individual hair is represented by a threedimensional curved cylinder the technique uses pixel blending combined with Z-buffer and shadow buffer information from the scene to yield a final anti-aliased image with soft shadows.(More)
In this paper, we present a user interaction methodology based on a six degree of freedom interactive input device called the SpaceballTM. This methodology is geared for computer graphics applications that require items to be positioned or displaced in three-dimensional space in a purely visual and esthetic fashion. When the Spaceball device is used in(More)
The mouse is the most commonly used laboratory animal, with more than 14 million mice being used for research each year in North America alone. The number and diversity of mouse models is increasing rapidly through genetic engineering strategies, but detailed characterization of these models is still challenging because most phenotypic information is(More)
In this paper, we present a user interaction methodology based on a six degree of freedom interactive input device called the SpaceballTM. This methodology is geared for computer graphics applications that require items to be positioned or displaced in three-dimensional space in a purely visual and esthetic fashion . When the Space ball device is used in(More)
The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mechanistic target of rapamycin (mTOR) pathway is one of the most commonly dysregulated signaling pathways that is linked to cancer development and progression, and its quantitative protein analysis holds the promise to facilitate patient stratification for targeted therapies. Whereas(More)
When quantifying endogenous plasma proteins for fundamental and biomedical research - as well as for clinical applications - precise, reproducible, and robust assays are required. Targeted detection of peptides in a bottom-up strategy is the most common and precise mass spectrometry-based quantitation approach when combined with the use of stable(More)
Filiform structures occur in the natural environment in various forms and embrace a wide variety of phenomena. They are, by definition, very thin threadlike objects that yield, in aggregate form, highly complex and somewhat nebulous volumes such as fur, hair and fibrous material. Larger and more detailed geometry such as grass, plants or tree branches may(More)
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