André G. Holzner

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One of the missions of the LEP program was the search for the Standard Model Higgs Boson. The skillful operation of the machine in the year 2000, the final year of operation, has allowed the four collaborations ALEPH, DELPHI, L3 and OPAL to collect 536 pb of data at center-of-mass energies of 206 GeV or higher. This data is used to probe the existence of(More)
Data from high-energy physics (HEP) experiments are collected with significant financial and human effort and are mostly unique. An inter-experimental study group on HEP data preservation and long-term analysis was convened as a panel of the International Committee for Future Accelerators (ICFA). The group was formed by large collider-based experiments and(More)
We describe the synthesis of 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides and demonstrate their utility as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event. These 2'-O-modified compounds were designed to possess the binding affinity of an RNA molecule towards a complementary RNA target with(More)
In the last running years, the four Large Electron Positron collider (LEP) experiments collected a combined luminosity of almost 2.5 fb −1 at √ s ≥ 189 GeV. This data was searched for invisibly decaying Higgs bosons produced in association with a Z boson. The channels with electrons, muons and hadrons were investigated. None of the experiments sees hints(More)
There is growing interest in the issues of preservation and re-use of the records of science, in the “digital era”. The aim of the PARSE.Insight project, partly financed by the European Commission under the Seventh Framework Program, is twofold: to provide an assessment of the current activities, trends and risks in the field of digital preservation of(More)
The Data Acquisition system of the Compact Muon Solenoid experiment at CERN assembles events at a rate of 100 kHz, transporting event data at an aggregate throughput of 100 GByte/s. We are presenting the design of the 2nd generation DAQ system, including studies of the event builder based on advanced networking technologies such as 10 and 40 Gbit/s Ethernet(More)
In the Standard Model (SM), the weak gauge bosons and fermions acquire mass through the Higgs mechanism. A lower limit on the SM Higgs mass of 114.4 GeV was obtained from the direct search at LEP. Although a single Higgs doublet is sufficient to explain the non-zero particle masses while keeping the theory SU(2) gauge invariant, several extensions to this(More)
The four LEP experiments ALEPH, DELPHI, L3 and OPAL successfully recorded ee collision data during the years 1989 to 2000. As part of the ordinary evolution in High Energy Physics, these experiments can not be repeated and their data is therefore unique. This article briefly reviews the data preservation efforts undertaken by the four experiments beyond the(More)
The DAQ system of the CMS experiment at CERN collects data from more than 600 custom detector Front-End Drivers (FEDs). During 2013 and 2014 the CMS DAQ system will undergo a major upgrade to address the obsolescence of current hardware and the requirements posed by the upgrade of the LHC accelerator and various detector components. For a loss-less data(More)
The CMS experiment’s online cluster consists of 2300 computers and 170 switches or routers operating on a 24-hour basis. This huge infrastructure must be monitored in a way that the administrators are pro-actively warned of any failures or degradation in the system, in order to avoid or minimize downtime of the system which can lead to loss of data taking.(More)