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In a comparative study of endometriosis and endometrium, specimens were taken from both endometriotic and endometrial tissue in 14 patients. Receptor assays and histological examinations were performed on both specimens. Cytosolic estrogen receptors (ERc) as well as cytosolic progesterone receptors (PRc) were detected in 9/14 and 12/12 cases of(More)
Twenty of 31 consecutive ultrasound examined patients with primary hyperparathyroidism were selected for treatment with ultrasound-guided percutaneous injection of ethanol (96%) into biopsy-verified solitary parathyroid tumours following a strict protocol with regard to dose, number of treatments and a minimum of 6 months follow-up. Of 18 patients(More)
OBJECTIVE The purpose of this study was to evaluate the incidence, diagnostic criteria and treatment of eosinophilic cystitis (EC) in Denmark during the period 1989-94. MATERIAL AND METHODS A questionnaire was sent to all Danish departments of surgery, urology and pathology. RESULTS Fifty-six cases of EC were diagnosed in the departments of surgery and(More)
Invasive carcinoma of the uterine cervix is a common neoplasm even in countries with extensive screening programmes of several years. The incidence rate per 100,000 is still around 18 in Denmark. The reasons for these persistently high rates of incidence despite various prophylactic measures are many and have been thoroughly discussed over recent years. It(More)
In 175 consecutive cases of ultrasonically detected focal liver lesions both cytological (CFNB) and histological (HFNB) fine needle biopsies were performed with two different 0.6 mm needles and evaluated twice and blindly by two examiners. The intra- and interobserver kappa values for reproducibility concerning a malignant diagnosis were higher for CFNB(More)
BACKGROUND Human neutrophil peptides (HNPs) were discovered as abundant antimicrobial peptides of azurophil granules. Later studies revealed that most HNPs were produced by myelocytes and metamyelocytes and secreted into the bone marrow plasma as the inert proforms, proHNPs. Despite the vast amounts of proHNPs released into bone marrow plasma, little has(More)
Ultrasound-guided, fine-needle tissue biopsies were performed in 60 suspected parathyroid tumours in 55 consecutive patients with biochemically proven hyperparathyroidism. The specimens were randomly arranged and re-read "blind" by two pathologists. The interobserver agreement, corrected for chance agreement, was 0.92 (= kappa coefficient). Twenty-three of(More)
Olfactomedin 4 (OLFM4) is a secreted glycoprotein predominantly expressed in bone marrow and gastrointestinal tissues. Aberrant expression of OLFM4 has been shown in several cancers. However, the clinical significance hereof is currently controversial. OLFM4 has been proposed as a candidate biomarker of gastrointestinal cancers. To address this, we(More)
A 63-year-old woman with necrolytic migratory erythema associated with a glucagonoma in the pancreas is described. The diagnosis was suggested on the basis of a characteristic lesion in skin biopsy. Infusion of somatostatin (25 micrograms/h) for 48 hours was followed by a rapid and almost complete healing of the skin eruptions. Serum glucagon was depressed(More)