Anders Eklund

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Division of Medical Informatics, Department of Biomedical Engineering, Linköping University, S-581 85 Linköping, Sweden; Division of Statistics and Machine Learning, Department of Computer and Information Science, Linköping University, S-581 83 Linköping, Sweden; Center for Medical Image Science and Visualization, Linköping University, S-581 83 Linköping,(More)
OBJECTIVE To investigate whether smoking and HLA-DR shared epitope (SE) genes may interact in triggering immune reactions to citrulline-modified proteins. METHODS In a case-control study involving patients with recent-onset rheumatoid arthritis (RA), we studied interactions between a major environmental risk factor (smoking), major susceptibility genes(More)
Little is known about the cancer risk following sarcoidosis. In a retrospective cohort study, we tested the hypothesis of an increased risk for malignant lymphomas, lung cancer as well as cancer in other organs frequently involved in sarcoidosis. Four hundred seventy-four patients from an incidence study 1966-1980 and 8,541 patients identified in the(More)
The validity of parametric functional magnetic resonance imaging (fMRI) analysis has only been reported for simulated data. Recent advances in computer science and data sharing make it possible to analyze large amounts of real fMRI data. In this study, 1484 rest datasets have been analyzed in SPM8, to estimate true familywise error rates. For a familywise(More)
Graphics processing units (GPUs) are used today in a wide range of applications, mainly because they can dramatically accelerate parallel computing, are affordable and energy efficient. In the field of medical imaging, GPUs are in some cases crucial for enabling practical use of computationally demanding algorithms. This review presents the past and present(More)
Tissue hardness is related to tissue composition, and this is often changed by disease. It is therefore of interest to measure the hardness in an objective and non-invasive way. A tactile sensor based on a vibrating piezoelectric ceramic element in a feedback loop is described. When the sensor touches an object it produces a frequency shift related to the(More)
In patients with idiopathic normal pressure hydrocephalus (INPH), the changes in brain function that take place in conjunction with improved behavioural performance after CSF drainage is still unknown. In this study, we use functional MRI (fMRI) to investigate the changes in cortical activity that accompany improved motor and cognitive performance after(More)
Fourteen healthy, nonsmoking subjects were exposed to swine dust while weighing pigs for 3 to 5 h in a swine-confinement building. All but one participant was previously unexposed to swine dust. Bronchoalveolar lavage (BAL) was performed and blood samples were drawn before and after exposure. Total dust and endotoxins were measured by air sampling in filter(More)
BACKGROUND Allergic asthma is caused by allergen-specific IgE and T-helper cell (Th) type 2 responses towards airborne allergens. The objective of this study was to investigate local and systemic regulatory mechanisms in the early asthmatic response to bronchial allergen provocation. METHODS Birch pollen-allergic patients with mild asthma (n = 13) and(More)