Learn More
Most great ape genetic variation remains uncharacterized; however, its study is critical for understanding population history, recombination, selection and susceptibility to disease. Here we sequence to high coverage a total of 79 wild- and captive-born individuals representing all six great ape species and seven subspecies and report 88.8 million single(More)
We present a hidden Markov model (HMM) for inferring gradual isolation between two populations during speciation, modelled as a time interval with restricted gene flow. The HMM describes the history of adjacent nucleotides in two genomic sequences, such that the nucleotides can be separated by recombination, can migrate between populations, or can coalesce(More)
Biotechnological improvements over the last decade has made it economically and technologically feasible to collect large DNA sequence data from many closely related species. This enables us to study the detailed evolutionary history of recent speciation and demographics. Sophisticated statistical methods are needed, however, to extract the information that(More)
  • 1