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The distribution of substance P (SP) - and calcitonin gene-related peptide (CGRP) - containing nerve fibers in the rat larynx was studied using immunohistochemistry. Double-labeling studies revealed a high degree of co-existence of SP- and CGRP-like immunoreactivity (LI) in the nerve fibers in the larynx. There was a considerable regional difference in the(More)
An endoneurial paraganglion located in the recurrent laryngeal nerve of the rat was found in 17 of 20 nerves studied. The median size of the paraganglia was estimated to be 0.8 X 10(6) micron 3. The number of type I like cells within a paraganglion ranged between 8 and 24. Altogether, 120 endoneurial dense-cored vesicle cells from 8 paraganglia were(More)
Sections of right or left recurrent laryngeal nerve (RLN), removed from patients with spastic dysphonia (SD) at the time of surgery, were studied using light and electron microscopy and were compared with control RLNs. In both groups, small, medium and large-sized myelinated nerve fibres were found in the RLN. Furthermore, numerous unmyelinated axons(More)
Paraganglia of the recurrent laryngeal nerve of rats exposed to hypoxia (10 +/- 0.5% O2) for 3 weeks became enlarged in volume by 2.6-fold. The volume densities of blood vessel lumen and endothelial cells were unchanged. The enlargement of the paraganglia was mainly attributed to hypertrophy of the dense-cored vesicle-containing cell. Concerning the profile(More)
  • M Lee, M Lenman, A Banaś, M Bafor, S Singh, M Schweizer +7 others
  • 1998
Acetylenic bonds are present in more than 600 naturally occurring compounds. Plant enzymes that catalyze the formation of the Delta12 acetylenic bond in 9-octadecen-12-ynoic acid and the Delta12 epoxy group in 12,13-epoxy-9-octadecenoic acid were characterized, and two genes, similar in sequence, were cloned. When these complementary DNAs were expressed in(More)
Oat (Avena sativa) is unusual in comparison with other cereals since there are varieties with up to 18% oil content. The lipid content and fatty acid composition in different parts of the grain during seed development were characterized in cultivars Freja (6% oil) and Matilda (10% oil), using thin-layer and gas chromatography, and light and electron(More)
The catecholamines in the recurrent and superior laryngeal nerves of the rat were assayed by high performance liquid chromatography. The nerves were shown to contain high levels of dopamine (1.9 +/- 0.6 and 2.3 +/- 0.4 pmol, respectively) and noradrenaline (1.3 +/- 0.3 and 0.9 +/- 0.2 pmol, respectively). No adrenaline could be detected in any of the(More)
A qualitative study of the nerve fiber composition of the recurrent laryngeal nerve of the rat was performed by light and electron microscopy. Various surgical denervation procedures were employed to determine the origin of the variously sized myelinated fibers and the unmyelinated axons present within the nerve. After extracranial vagotomy all myelinated(More)
A quantitative study by light and electron microscopy of the recurrent laryngeal nerve (RLN) of the rat has been performed. The diameter of the myelinated fibers displayed a bimodal pattern, with a pronounced peak at 2-3 microns, and with a second peak at 4.5-7 microns. The number of small fibers was reduced at the termination of the nerve, indicating that(More)
In contrast to the increased content of dopamine and norepinephrine in rat carotid body during hypoxia (10% O2 in nitrogen) for 3 and 21 days, hypercapnia (8% CO2 in air) for 21 days failed to alter the catecholamine concentrations. DOPAC content was elevated in hypoxia whereas there were no significant changes in hypercapnia. This finding supports the view(More)