Anchal Singh

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NeuroAIDS is becoming a major health problem among AIDS patients and long-term HIV survivors. As per 2009 estimates of UNAIDS report, more than 34 million people have been infected with HIV out of which ≥ 50% show signs and symptoms of neuropsychiatric disorders. These disorders affect central nervous system (CNS) and peripheral nervous systems (PNS). CNS(More)
Fingolimod (FTY720) is asphingosine-1-phosphate receptor modulator,[3,5] which is present on the surface of thymocytes, lymphocytes, and neural cells.[3,5] Phosphorylated fingolimod acts as a functional antagonist of the sphingosine-1-phosphate receptor, inducing receptor internalization and rendering T and B cells insensitive to a signal necessary for come(More)
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