Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications.
The earliest visible indications for the transition to embryos in mammalian eggs, known as egg activation, are cortical granules exocytosis (CGE) and resumption of meiosis (RM); these events are… (More)
Prior to fertilization, the spindle of vertebrate eggs must remain stable and well organized during the second meiotic meta-phase arrest (MII). In a previous study we have determined that the… (More)
Following penetration of the zona pellucida, the mammalian spermatozoon binds and fuses with the egg plasma membrane, thereby fertilizing the egg that is still arrested at the second metaphase.… (More)
The mature egg arrested at its second metaphase is a rather quiet cell, and possesses a pre-set developmental program. A sequence of biochemical events that leads to the rapid embryonic mitotic… (More)