Anastasia Papavasiliou

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Particle filters are Monte Carlo methods that aim to approximate the optimal filter of a partially observed Markov chain. In this paper, we study the case in which the transition kernel of the Markov chain depends on unknown parameters: we construct a particle filter for the simultaneous estimation of the parameter and the partially observed Markov chain(More)
RNA editing is a mutational mechanism that specifically alters the nucleotide content in transcribed RNA. However, editing rates vary widely, and could result from equivalent editing amongst individual cells, or represent an average of variable editing within a population. Here we present a hierarchical Bayesian model that quantifies the variance of editing(More)
We propose a particle filter for the estimation of a partially observed Markov chain that has a non dynamic component. Such systems arise when we include unknown parameters or when we decompose non ergodic systems to their ergodic classes. Our main assumption is that the value of the non dynamic component determines the limiting distribution of the(More)
The solution of a (stochastic) differential equation can be locally approximated by a (stochastic) expansion. If the vector field of the differential equation is a polynomial, the corresponding expansion is a linear combination of iterated integrals of the drivers and can be calculated using Picard Iterations. However, such expansions grow exponentially(More)
The paper is split in two parts: first, we construct the exact likelihood for a discretely observed rough differential equation, driven by a piecewise linear path. In the second part, we use this likelihood in order to construct an approximation to the likelihood for a discretely observed rough differential equation. Finally, We show that the approximation(More)
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