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The epidemic of chronic kidney disease in Nicaragua (Mesoamerican nephropathy) has been linked with recurrent dehydration. Here we tested whether recurrent dehydration may cause renal injury by activation of the polyol pathway, resulting in the generation of endogenous fructose in the kidney that might subsequently induce renal injury via metabolism by(More)
We investigated the ability of serum uric acid (SUA) to predict laboratory tumor lysis syndrome (LTLS) and compared it to common laboratory variables, cytogenetic profiles, tumor markers and prediction models in acute myeloid leukemia patients. In this retrospective study patients were risk-stratified for LTLS based on SUA cut-off values and the(More)
On the application of optical tweezers and electro-rotation to study rotational dynamics of flagellar motors The bacterial flagellar motor is a rotary molecular engine driven by an electrochemical gradient; which turns a helical filament generating the thrust enabling the bacteria to swim. The mechanism of torque generation has been described by different(More)
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