Anake Pomprapa

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INTRODUCTION Automatic ventilation for patients with respiratory failure aims at reducing mortality and can minimize the workload of clinical staff, offer standardized continuous care, and ultimately save the overall cost of therapy. We therefore developed a prototype for closed-loop ventilation using acute respiratory distress syndrome network (ARDSNet)(More)
Purpose – The purpose of this paper is to develop an automatic control system for mechanical ventilation therapy based on the open lung concept (OLC) using artificial intelligence. In addition, mean arterial blood pressure (MAP) is stabilized by means of a decoupling controller with automated noradrenaline (NA) dosage to ensure adequate systemic perfusion(More)
The aim is to provide better understanding of carbon dioxide ( $$\mathrm{CO}_2$$ CO 2 ) elimination during ventilation for both the healthy and atelectatic condition, derived in a pressure-controlled mode. Therefore, we present a theoretical analysis of $$\mathrm{CO}_2$$ CO 2 elimination of healthy and diseased lungs. Based on a single-compartment model,(More)
In this paper, a novel approach to control end-tidal CO2 in mechanically ventilated patients is presented. Assuming a homogeneous lung model, a regulation of arterial CO2 tension in blood can be achieved non-invasively using L1 adaptive control with the aid of an extremum seeking method to set the proper respiratory rate. Using these integrated approaches,(More)
Adjustable compliance or variable stiffness actuators comprise an additional element to elastically decouple the actuator from the load and are increasingly applied to human-centered robotic systems. The advantages of such actuators are of paramount importance in rehabilitation robotics, where requirements demand safe interaction between the therapy system(More)
In this work, a medical expert system is further developed for automatic ventilation therapy based on the well-known ARDSNet protocol by imposing additional dynamical constraints. This protocol-driven approach strengthens the overall treatment of patients with acute lung injury in terms of improving oxygenation dynamics. The proposed dynamics of quick(More)