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OBJECTIVE The association between high-sensitivity C-reactive protein (hs-CRP) and alanine aminotransferase (ALT) with clinical/metabolic variables was evaluated in overweight Brazilian children and adolescents. STUDY DESIGN Oral glucose tolerance test was performed in 407 students (273 overweight/obese, 11.3 +/- 3.1 y). Measurements included body mass(More)
BACKGROUND The relationship between coronary artery disease (CAD) and dyslipidemia in acute coronary syndromes has been rarely demonstrated in clinical and epidemiological studies. OBJECTIVE To evaluate the association between lipid profile and severity of CAD in patients with acute coronary syndrome without ST-segment elevation. METHODS In this(More)
Data on dyslipidemia in type 1 diabetes is scarce. The authors aimed to evaluate the lipid profile in patients with type 1 diabetes and its correlation to glycemic control. Ninety-four subjects (53.2% males), aged 15.4+/-4.7 (3.6-21.9 years), with disease duration of 5.0+/-3.6 years (0.3-17 years) were evaluated for heart rate, blood pressure, height, and(More)
OBJECTIVE To assess the frequency of cardiovascular risk factors in the rural community of Cavunge, in the Brazilian state of Bahia. METHODS A cross-sectional study was carried out with 160 individuals (age>19 years) randomly drawn from those listed in the population census of the Cavunge Project. The following parameters were studied: arterial(More)
OBJECTIVE Metabolic syndrome (MS) is on the rise in youth. As high-sensitivity C-reactive protein (hs-CRP) is associated with cardiovascular/metabolic disorders, we evaluated the association between MS and its components and hs-CRP in a sample of Brazilian overweight and obese youth. METHODS AND PROCEDURES A total of 407 students (229 girls, 273 with(More)
OBJECTIVE The literature on palm oil as a cholesterol-raising oil is conflicting, requiring further studies. This study tested the influence of a palm oil-rich diet on plasma lipids of healthy young individuals. METHODS Thirty-four medical students, 18-26 y old, with a total cholesterol level <200 mg/dL, high-density lipoprotein cholesterol (HDL-C) level(More)
Antiretroviral therapy (ART) in HIV-infected patients has been associated with an increased risk of cardiovascular disease. This study evaluates vascular endothelial dysfunction of the peripheral circulation in Brazilian HIV-infected subjects on ART or naive to ART compared to a control group matched for age and body mass index (BMI). We performed a(More)
Control of risk factors for coronary heart disease secondary prevention is still very unsatisfactory. This study assessed 104 patients referred by cardiologists to discover how carefully National Cholesterol Education Program II recommendations were being followed. Average age of the cohort was 60.9+/-10.8 years, and 67.3% were men. A total of 57(54.8%)(More)
BACKGROUND The effect of statins on the endothelial function in humans remains under discussion. Particularly, it is still unclear if the improvement in endothelial function is due to a reduction in LDL-cholesterol or to an arterial pleiotropic effect. OBJECTIVE To test the hypothesis that modulation of the endothelial function promoted by statins is(More)