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  • Ana M. Martins, Quynh P. Pham, +4 authors Antonios G. Mikos
  • Biology, Medicine
  • Tissue engineering. Part A
  • 2009 (First Publication: 1 August 2009)
  • This work proposes the use of nonporous, smart, and stimulus responsive chitosan-based scaffolds for bone tissue engineering applications. The overall vision is to use biodegradable scaffolds basedContinue Reading
  • Ana M. Martins, Anita Saraf, +4 authors Rui Luís Reis
  • Materials Science, Medicine
  • Journal of biomedical materials research. Part A
  • 2010
  • Previous studies have shown that alpha-amylase and lipase are capable of enhancing the degradation of fiber meshes blends of starch and poly(epsilon-caprolactone) (SPCL) under dynamic conditions, andContinue Reading
  • Ana M. Martins, Quynh P. Pham, +6 authors Antonios G. Mikos
  • Medicine, Biology, Materials Science
  • Tissue engineering. Part A
  • 2009 (First Publication: 1 February 2009)
  • The present work studies the influence of hydrolytic enzymes (alpha-amylase or lipase) on the degradation of fiber mesh scaffolds based on a blend of starch and poly(epsilon-caprolactone) (SPCL) andContinue Reading
  • Ana M. Martins, Marina I. Santos, Helena S Azevedo, Patrícia B. Malafaya, Rui Luís Reis
  • Materials Science, Medicine
  • Acta biomaterialia
  • 2008 (First Publication: 1 November 2008)
  • This work describes the development of a biodegradable matrix, based on chitosan and starch, with the ability to form a porous structure in situ due to the attack by specific enzymes present in theContinue Reading
  • Ana M. Martins, James D. Kretlow, +7 authors Rui Luís Reis
  • Materials Science, Medicine
  • Journal of biomedical materials research. Part A
  • 2012 (First Publication: 1 March 2012)
  • This study used a rat subcutaneous implantation model to investigate gradual in situ pore formation in a self-regulating degradable chitosan-based material, which comprises lysozyme incorporated intoContinue Reading