Ana Luiza Bastos

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OBJECTIVES The extracellular matrix is a key element in penile function and pathology, yet little is known of its development. Herein we investigated the morphological organization of collagen and elastin in the corpora cavernosa and tunica albuginea of human fetuses. MATERIAL AND METHODS The penises from 5 fresh human fetuses at 28 weeks postconception(More)
In a toluidine blue dye (British Drug Houses, batch no. 651880), we report a purple chromato­ graphic fraction (Rf—0,55) with a spectral absorption peak at 622 m/u, which has the property to induce immediate bright yellow fluorescence (primary inducible fluorescence) in cytoplasmic gra­ nules of tumor cells. The cells are unfixed, supravital stained and(More)
PURPOSE We investigated the composition of collagen and glycosaminoglycans (GAGs) in the corpus cavernosum (CC) and tunica albuginea (TA) of normal human penises. MATERIALS AND METHODS Penises were obtained from a 6-month-old child (group 1), a 2-year-old child (group 2), 18 to 34-year-old adults (group 3), 37 to 53-year-old adults (group 4) and 22(More)
PURPOSE We analyzed the development of the area of the penis and erectile structures (corpora cavernosa and corpus spongiosum) and the thickness of the tunica albuginea during the fetal period (13 to 36 weeks after conception) in humans to establish normative patterns of growth. MATERIALS AND METHODS We studied 56 male human fetuses at 13 to 36 weeks(More)
BACKGROUND The penile erectile tissue has a complex microscopic anatomy with important functions in the mechanism of penile erection. The knowledge of such structures is necessary for understanding the normal physiology of the adult penis. Therefore, it is important to know the changes of these penile structures during fetal development. This study aims to(More)
The extracellular matrix is an important element in penile function and pathology, although little is known about its components in human glans. This study evaluates the morphological organization and volumetric density of elastic fibers in the glans penis of young men without any evidence of urogenital disease at autopsy or medical history. Penile glans(More)