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We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow fever and dengue fever, which at approximately 1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae. Nearly 50% of the Ae. aegypti genome consists of transposable elements. These contribute to a factor of approximately(More)
Leptospirosis is a worldwide zoonotic infection of human and veterinary concern. Caused by pathogenic spirochetes of the genus Leptospira, the disease presents greater incidence in tropical and subtropical regions. The identification of proteins that could be involved in the bacteria host interactions may facilitate the search for immune protective(More)
Chinese hamster V79 cells were transfected with human transferrin receptor cDNA, lacking the 3' untranslatable regulatory sequence. One of the clones obtained was investigated completely. It exhibited the cDNA sequences recombined into the genome, transcribed the corresponding mRNA and became partially constitutive in iron uptake from transferrin. The rate(More)
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