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- Angelo Rosa, Jaime Lin, João Batista Calixto, Adair Roberto Soares dos Santos, Ana Lúcia S Rodrigues
- Behavioural brain research
- 2003
This study investigated the involvement of NMDA receptors and the L-arginine-nitric oxide (NO) pathway in the antidepressant-like effects of zinc in the forced swimming test (FST). The immobility… (More)
- Manuella Pinto Kaster, Vinícius de Maria Gadotti, João Batista Calixto, Adair R. S. Santos, Ana Lúcia S Rodrigues
- Neuropharmacology
- 2012
Pro-inflammatory cytokines are implicated in the pathogenesis of depression. However, few animal models of cytokine-induced depression well characterized regarding its response to antidepressants are… (More)
Agmatine produces an antidepressant-like effect when assessed in the forced swimming test (FST) and in the tail suspension test (TST) in mice (dose range 0.01-50 mg/kg, i.p.), without accompanying… (More)
- Ricardo Wabner Binfaré, Angelo Rosa, Kelly Ribas Lobato, Adair R. S. Santos, Ana Lúcia S Rodrigues
- Progress in neuro-psychopharmacology & biological…
- 2009
Ascorbic acid is highly concentrated in the brain, being considered as a neuromodulator. This study investigated the effect of ascorbic acid in the tail suspension test (TST) and in the forced… (More)
- Mauricio P Cunha, Daniele Guilhermano Machado, Luis E. B. Bettio, Juliano C. Capra, Ana Lúcia S Rodrigues
- Progress in neuro-psychopharmacology & biological…
- 2008
The antidepressant-like effect of zinc has been shown in several animal models of depression. In this study, zinc chloride (ZnCl2) was given alone or in combination with different classes of… (More)
- Nice Sarmento Arteni, L. O. Pereira, Ana Lúcia S Rodrigues, Daniel Lavinsky, Matilde E Achaval, C. A. Netto
- Behavioural brain research
- 2010
Neonatal cerebral hypoxia-ischemia (HI) is an important cause of neurological deficits. The Levine-Rice model of unilateral HI is a useful experimental tool, but the resulting brain damage is mainly… (More)
- Daniele Guilhermano Machado, Luis E. B. Bettio, +4 authors Ana Lúcia S Rodrigues
- Progress in neuro-psychopharmacology & biological…
- 2009
Rosemary, Rosmarinus officinalis L. (Labiatae) has several therapeutic applications in folk medicine in curing or managing a wide range of diseases, including depression. In this study, the effect of… (More)
- Fabiano Mendes de Cordova, Ana Lúcia S Rodrigues, +4 authors Rodrigo Bainy Leal
- Brain research
- 2004
Lead (Pb(2+)) is widely recognized as a neurotoxicant whose mechanisms of action are not completely established. We have previously demonstrated that Pb(2+) can activate the p38(MAPK) pathway and… (More)
- Rúbia C Almeida, Cristiane S Felisbino, Manuela López, Ana Lúcia S Rodrigues, Nelson Horácio Gabilan
- Behavioural brain research
- 2006
This study investigated the involvement of the L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway in the antidepressant-like effect of an acute administration of memantine in… (More)
- Patricia S Brocardo, Josiane Budni, Manuella Pinto Kaster, Adair R. S. Santos, Ana Lúcia S Rodrigues
- Neuropharmacology
- 2008
Clinical studies have shown that folic acid plays a role in the pathophysiology of depression. However, very few studies have investigated its effect in behavioral models of depression. Hence, this… (More)