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Constitutive overexpression of human telomerase reverse transcriptase but not c-myc blocks terminal differentiation in human HaCaT skin keratinocytes.
Formation of a well structured epidermis strictly depends on a tight balance between proliferation and differentiation. Accordingly, telomerase, which is restricted to proliferating cells, isExpand
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Tissue context-activated telomerase in human epidermis correlates with little age-dependent telomere loss.
Telomerase- and telomere length regulation in normal human tissues is still poorly understood. We show here that telomerase is expressed in the epidermis in situ independent of age but was repressedExpand
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A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes
By interfering with the TGFβ/Smad pathway in the human HaCaT keratinocytes, this study provides novel insights into the role of Smad signaling for regular tissue homeostasis and demonstrates itsExpand
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ESTUDIO COMPARATIVO DE LA UTILIDAD DE LA POLISOMNOGRAFÍA DOMICILIARIA FRENTE A LA HOSPITALARIA COMO MÉTODO DIAGNÓSTICO DEL SÍNDROME DE APNEA HIPOPNEA DEL SUEÑO
Proyecto SOCALPAR 2016, Proyecto VA037U16 de la Junta de Castilla y Leon y FEDER; Contrato Juan de la Cierva MINECO.