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Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children
TLDR
Monitoring the concentrations of folate would be more helpful for evaluating hyperhomocysteinemia and for preventing cardiovascular disease.
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Polymorphism C776G in the transcobalamin II gene and homocysteine, folate and vitamin B12 concentrations. Association with MTHFR C677T and A1298C and MTRR A66G polymorphisms in healthy children.
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Evaluation of mild hyperhomocysteinemia during the development of atherosclerosis in apolipoprotein E-deficient and normal mice.
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Folate, Vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center
TLDR
The results suggest that folate deficiency is practically nonexistent in the post-folic acid fortification era in the subgroups evaluated, however, screening for vitamin B12 deficiency may be particularly relevant in the elderly.
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Polymorphisms in the CBS gene and homocysteine, folate and vitamin B12 levels: Association with polymorphisms in the MTHFR and MTRR genes in Brazilian children
TLDR
Analysis of Hcy, B12 and folate, according to the combination of the different genotypes of the C677T and A1298C MTHFR, A66G MTRR, and 844ins68 CBS showed that the 677TT/1298AA/68WW genotype is associated with an increase in Hcy.
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