Sort by:

• Highly Influential Citations
• Citations
• Acceleration
• Velocity
• Recency

Learn More

1,25-Dihydroxyvitamin D3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

• Tom L. Van Belle, An-Sofie Vanherwegen, +6 authors Matthias G von Herrath
• PloS one
• 2014

The emergence of regulatory T cells (Tregs) as central mediators of peripheral tolerance in the immune system has led to an important area of clinical investigation to target these cells for the… (More)

Vitamin D endocrinology on the cross-road between immunity and metabolism.

• An-Sofie Vanherwegen, Conny A. Gysemans, Chantal Mathieu
• Molecular and cellular endocrinology
• 2017

The effects of vitamin D on the immune function have been recognized for more than a quarter of a century. However, our understanding of the multifactorial nature of the effects of vitamin D at the… (More)

Regulation of Immune Function by Vitamin D and Its Use in Diseases of Immunity.

• An-Sofie Vanherwegen, Conny A. Gysemans, Chantal Mathieu
• Endocrinology and metabolism clinics of North…
• 2017

Evidence exists for a role for vitamin D and its active metabolites in modulating immune functions. In animal models, vitamin D deficiency is associated with a higher risk for autoimmunity in… (More)

Dendritic cell metabolism: immunity and tolerance.

• An-Sofie Vanherwegen, Conny A. Gysemans, Lut Overbergh
• Oncotarget
• 2015

1,25-Dihydroxyvitamin D3 promotes tolerogenic dendritic cells with functional migratory properties in NOD mice.

• Gabriela Bomfim Ferreira, Conny A. Gysemans, +8 authors Chantal Mathieu
• Journal of immunology
• 2014

The biologically active form of vitamin D, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], is able to promote the generation of tolerogenic mature dendritic cells (mDCs) with an impaired ability to activate… (More)

Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways.

• Gabriela Bomfim Ferreira, An-Sofie Vanherwegen, +13 authors Chantal Mathieu
• Cell reports
• 2015

Metabolic switches in various immune cell subsets enforce phenotype and function. In the present study, we demonstrate that the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3),… (More)

The phenotype and function of murine bone marrow-derived dendritic cells is not affected by the absence of VDR or its ability to bind 1α,25-dihydroxyvitamin D3.

• An-Sofie Vanherwegen, Gabriela Bomfim Ferreira, +5 authors Chantal Mathieu
• The Journal of steroid biochemistry and molecular…
• 2016

The nuclear vitamin D receptor (VDR) is generally recognized as a ligand-dependent transcription factor that mediates the actions of its natural ligand, 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) on… (More)

• ‹
• 1
• ›