An-Sofie Lemmens

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The induction of experimental arthritis in rhesus monkeys was studied by intradermal immunization of bovine type II collagen and antigens derived from Mycobacterium tuberculosis, Streptococcus pyogenes, and Eubacterium aerofaciens. The tested bacterial antigens proved to be not arthrogenic. Bovine type II collagen induced clinical arthritis in 50% of the(More)
OBJECTIVE To compare the effects of azathioprine and methotrexate on progression of radiologic damage in patients with rheumatoid arthritis. DESIGN Double-blind, randomized 48-week trial. PATIENTS Sixty-four patients with active rheumatoid arthritis who either have not responded to or who have reacted with side effects to at least parenteral gold and(More)
Environmental pollution in the Gulf of Guinea (GOG) coastal zone has caused eutrophication and oxygen depletion in the lagoon systems, particularly around the urban centres, resulting in decreased fish (reproduction) levels and waterborne diseases. A pollution sources assessment was undertaken by six countries in the region as a first step in defining a(More)
Although indomethacin is effective in preventing heterotopic ossification (HO) after total hip arthroplasty (THA) when used for 8 to 14 days, side effects are frequently observed. We conducted a prospective, nonrandomized pilot study of prophylaxis for HO in THA using indomethacin for 3 days. We used a 2-stage design for phase 2 clinical data, based on(More)
Ninety-five patients underwent primary total hip arthroplasty and routinely received ibuprofen for 5 days as prophylaxis for heterotopic ossification. This group was compared with a group of 99 patients who received indomethacin for 7 days as prophylaxis. After a follow-up of 1 year, the incidence of heterotopic ossification in the ibuprofen group was(More)
To analyse the validity of Cyriax's concept of the "capsular pattern" in the diagnosis of osteoarthritis (OA) of hip and knee, data on 200 patients were analysed. The capsular pattern with limitations of medial rotation, flexion, and abduction, was not present as a distinct pattern in patients with OA of the hip. In patients with OA of the knee, an(More)
The start of a new millennium asks for sustainable products and production processes. The educational programme for engineers should therefore contain the tools for sustainable design. A new modern course called ‘Technology and Sustainability’ is developed to introduce these tools in relation to the concepts of sustainable technology development. It is a(More)
 A novel immunochromatographic membrane-based assay for the detection of specific IgG antibodies to Mycobacterium tuberculosis was evaluated in patients with active tuberculosis in a low-prevalence population. The sensitivity of the test for detecting active tuberculosis was 41.5% (17/41 patients positive); its specificity in a group of patients with other(More)
The induction of experimental arthritis in rhesus monkeys was studied by intradermal immunization of bovine type II collagen and antigens derived fromMycobacterium tuberculosis, Streptococcus pyogenes, andEubacterium aerofaciens. The tested bacterial antigens proved to be not arthritogenic. Bovine type II collagen induced clinical arthritis in 50% of the(More)