An Hua Huang

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Exercise training augments flow-dependent dilation in rat skeletal muscle arterioles. Role of endothelial nitric oxide and prostaglandins.

A. E. Koller, An Hua Huang, Dong Sun, Gabor Kaley
Circulation research
1995

We aimed to test the hypothesis that as a consequence of short-term daily exercise, flow (shear stress)-dependent dilation and its mediation by the endothelium are altered in skeletal muscle… (More)

Short-term daily exercise activity enhances endothelial NO synthesis in skeletal muscle arterioles of rats.

Dong K. Sun, An Hua Huang, A. E. Koller, Gabor Kaley
Journal of applied physiology
1994

We aimed to test the hypothesis that as a consequence of short-term daily bouts of exercise the control of arteriolar smooth muscle by endothelium is altered. Rats ran on a treadmill once a day, 5… (More)

Corelease of nitric oxide and prostaglandins mediates flow-dependent dilation of rat gracilis muscle arterioles.

A. E. Koller, Dong Sun, An Hua Huang, Gabor Kaley
The American journal of physiology
1994

We have studied the mechanisms responsible for the mediation of flow (shear stress)-induced dilation of isolated arterioles of rat gracilis muscle. Active diameter of arterioles at a constant… (More)

Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats.

Dong K. Sun, An Hua Huang, +6 authors Gabor Kaley
American journal of physiology. Heart and…
2004

We hypothesized that aging is characterized by a reduced release of nitric oxide (NO) in response to shear stress in resistance vessels. Mesenteric arterioles and arteries of young (6 mo) and aged… (More)

High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.

Zoltan Ungvari, Anna Csiszár, An Hua Huang, Pawel M. Kaminski, Michael S. Wolin, A. E. Koller
Circulation
2003

BACKGROUND Oxidative stress seems to be present in all forms of hypertension. Thus, we tested the hypothesis that high intraluminal pressure (Pi) itself, by activating vascular oxidases, elicits… (More)

Gender-specific compensation for the lack of NO in the mediation of flow-induced arteriolar dilation.

Yonghua Wu, An Hua Huang, Dong Sun, John R Falck, A. E. Koller, Gabor Kaley
American journal of physiology. Heart and…
2001

Flow-induced dilation of gracilis muscle arterioles was examined in both genders of control rats and rats chronically treated with N(omega)-nitro-L-arginine methyl ester (L-NAME). After L-NAME… (More)

Treatment of hypertension with ascorbic acid

Stephen J Duffy, Noyan Gokce, +4 authors Joseph A. Vita
The Lancet
1999

In a randomised, double-blind, placebo-controlled study we showed that treatment of hypertensive patients with ascorbic acid lowers blood pressure. Further studies of ascorbic acid to treat… (More)

EDRF-mediated shear-induced dilation opposes myogenic vasoconstriction in small rabbit arteries.

Ulrich Pohl, K Herlan, An Hua Huang, Eberhard Bassenge
The American journal of physiology
1991

In small saline-perfused rabbit mesenteric arteries (diam 221 +/- 4 microns, means +/- SE; n = 48) in situ, the interactions of endothelium-derived relaxing factor (EDRF)-mediated flow-dependent… (More)

Aging enhances pressure-induced arterial superoxide formation.

Azita Jacobson, Changdong Yan, +6 authors Dong Sun
American journal of physiology. Heart and…
2007

The purpose of this study was to investigate the mechanisms that regulate superoxide (O(2)(*-)) production as a function of an acute elevation of intravascular pressure and age. Mesenteric arteries… (More)

Development of nitric oxide and prostaglandin mediation of shear stress-induced arteriolar dilation with aging and hypertension.

A. E. Koller, An Hua Huang
Hypertension
1999

We hypothesized that during hypertension, the impairment of mediation of shear stress-induced dilation by nitric oxide (NO) is due to the prevailing hemodynamic forces, and that mediation of this… (More)

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