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Introduction Trafficking of women and children for the sex industry and for labor is prevalent in all regions of the United States. An estimated 45,000 to 50,000 women and children 1 are trafficked annually to the United States, 2 primarily by small crime rings and loosely connected criminal networks. The trafficked victims have traditionally come from(More)
We previously observed that the TGFbeta-Par6 pathway mediates loss of polarity and apoptosis in NMuMG cells. Here we investigate the contribution of Par6 versus TGFbeta receptor I activation to TGFbeta-induced apoptosis in association with changes in apico-basal polarity. We focus on the effect of Par6 activation on alpha6beta4 integrin expression and(More)
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