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Role of mammalian Mre11 in classical and alternative non-homologous end joining
The mammalian Mre11–Rad50–Nbs1 (MRN) complex coordinates double-strand break signaling with repair by homologous recombination and is associated with the H2A.X chromatin response to double-strandExpand
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Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.
Phosphorylated histone H2AX ("gamma-H2AX") recruits MDC1, 53BP1, and BRCA1 to chromatin near a double-strand break (DSB) and facilitates efficient repair of the break. It is unclear to what extentExpand
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BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks
Replication fork stalling can promote genomic instability, predisposing to cancer and other diseases. Stalled replication forks may be processed by sister chromatid recombination (SCR), generatingExpand
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BRCA1 and CtIP suppress long tract gene conversion between sister chromatids
BRCA1 controls early steps of the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination, but has no known role following Rad51-mediated synapsis. Here we show that BRCA1Expand
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XRCC2 and XRCC3 Regulate the Balance between Short- and Long-Tract Gene Conversions between Sister Chromatids
ABSTRACT Sister chromatid recombination (SCR) is a potentially error-free pathway for the repair of DNA lesions associated with replication and is thought to be important for suppressing genomicExpand
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Subjective memory and mood of Hong Kong Chinese adults with epilepsy
Clinicians are often confronted with the self-report of memory difficulties by patients. This study explored the possible correlates of subjective memory in 67 adult Chinese patients with epilepsy inExpand
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The southwestern surgical congress multi-center trial on suspected common duct stones.
BACKGROUND Choledocholithiasis is present in up to 15% of cholecystectomy patients. Treatment can be surgical, endoscopic, or via interventional radiology. We hypothesized significant heterogeneityExpand
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Planarizing ARs for dual-damascene processing
Via fill performance of AR7 (KrF anti-reflectant) and a prototype 193nm anti-reflectant were measured for 600 and 1000 nm deep vias in thermal oxide. Simple fitting functions were found which gaveExpand
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BRCA 1 and CtIP suppress long tract gene conversion
BRCA1 controls early steps of the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination, but has no known role following Rad51-mediated synapsis. Here we show that BRCA1Expand
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