Amy Grove

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BACKGROUND Clinical guidelines in orthopaedic surgery aim to improve the efficiency, quality and outcomes of patient care by ensuring that treatment recommendations are based on the best available evidence. The simple provision of guidelines, however, does not ensure fidelity or guarantee their uptake and use in surgical practice. Research exploring the(More)
BACKGROUND Aspirin has been recommended for primary prevention of cardiovascular disease (CVD) and cancer, but overall benefits are unclear. We aimed to use novel methods to re-evaluate the balance of benefits and harms of aspirin using evidence from randomised controlled trials, systematic reviews and meta-analyses. METHODS AND FINDINGS Data sources(More)
UNLABELLED Most people who die in hospital do so with a DNACPR order in place, these orders are the focus of considerable debate. AIM To identify factors, facilitators and barriers involved in DNACPR decision-making and implementation. METHODS All study designs and interventions were eligible for inclusion. Studies were appraised guided by CASP tools. A(More)
BACKGROUND Neurolinguistic programming (NLP) in health care has captured the interest of doctors, healthcare professionals, and managers. AIM To evaluate the effects of NLP on health-related outcomes. DESIGN AND SETTING Systematic review of experimental studies. METHOD The following data sources were searched: MEDLINE, PsycINFO, ASSIA, AMED, CINAHL,(More)
OBJECTIVES To investigate types of evidence used by healthcare commissioners when making decisions and whether decisions were influenced by commissioners' experience, personal characteristics or role at work. DESIGN Cross-sectional survey of 345 National Health Service (NHS) staff members. SETTING The study was conducted across 11 English Primary Care(More)
BACKGROUND Prophylactic aspirin has been considered to be beneficial in reducing the risks of heart disease and cancer. However, potential benefits must be balanced against the possible harm from side effects, such as bleeding and gastrointestinal (GI) symptoms. It is particularly important to know the risk of side effects when aspirin is used as primary(More)
OBJECTIVE To compare 10 year revision rates for frequently used types of primary total hip replacement to inform setting of a new benchmark rate in England and Wales that will be of international relevance. DESIGN Retrospective cohort study. SETTING National Joint Registry. PARTICIPANTS 239 000 patient records. MAIN OUTCOME MEASURES Revision rates(More)
BACKGROUND Advanced heart failure (HF) is a debilitating condition for which heart transplant (HT) offers the best treatment option. However, the supply of donor hearts is diminishing and demand greatly exceeds supply. Ventricular assist devices (VADs) are surgically implanted pumps used as an alternative to transplant (ATT) or as a bridge to transplant(More)
BACKGROUND Evolvements in the design, fixation methods, size, and bearing surface of implants for total hip replacement (THR) have led to a variety of options for healthcare professionals to consider. The need to determine the most optimal combinations of THR implant is warranted. This systematic review evaluated the clinical effectiveness of different(More)
BACKGROUND The treatment for a cardiac arrest, cardiopulmonary resuscitation (CPR), may be lifesaving following an acute, potentially reversible illness. Yet this treatment is unlikely to be effective if cardiac arrest occurs as part of the dying process towards the end of a person's natural life. Do not attempt CPR (DNACPR) decisions allow resuscitation to(More)