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BACKGROUND Aspirin has been recommended for primary prevention of cardiovascular disease (CVD) and cancer, but overall benefits are unclear. We aimed to use novel methods to re-evaluate the balance of benefits and harms of aspirin using evidence from randomised controlled trials, systematic reviews and meta-analyses. METHODS AND FINDINGS Data sources(More)
OBJECTIVES To investigate types of evidence used by healthcare commissioners when making decisions and whether decisions were influenced by commissioners' experience, personal characteristics or role at work. DESIGN Cross-sectional survey of 345 National Health Service (NHS) staff members. SETTING The study was conducted across 11 English Primary Care(More)
BACKGROUND Neurolinguistic programming (NLP) in health care has captured the interest of doctors, healthcare professionals, and managers. AIM To evaluate the effects of NLP on health-related outcomes. DESIGN AND SETTING Systematic review of experimental studies. METHOD The following data sources were searched: MEDLINE, PsycINFO, ASSIA, AMED, CINAHL,(More)
OBJECTIVE To compare 10 year revision rates for frequently used types of primary total hip replacement to inform setting of a new benchmark rate in England and Wales that will be of international relevance. DESIGN Retrospective cohort study. SETTING National Joint Registry. PARTICIPANTS 239 000 patient records. MAIN OUTCOME MEASURES Revision rates(More)
BACKGROUND Many health systems across the globe have introduced arrangements to deny payment for patients readmitted to hospital as an emergency. The purpose of this study was to develop an exploratory categorisation based on likely causes of readmission, and then to assess the prevalence of these different types. METHODS Retrospective analysis of 82(More)
BACKGROUND Evolvements in the design, fixation methods, size, and bearing surface of implants for total hip replacement (THR) have led to a variety of options for healthcare professionals to consider. The need to determine the most optimal combinations of THR implant is warranted. This systematic review evaluated the clinical effectiveness of different(More)
OBJECTIVES To undertake an assessment of the association between coproduction and satisfaction with decisions made for local healthcare communities. DESIGN A coproduction scale was developed and tested to measure individual National Health Service (NHS) commissioners' satisfaction with commissioning decisions. SETTING 11 English Primary Care Trusts in(More)
BACKGROUND Clinical guidelines in orthopaedic surgery aim to improve the efficiency, quality and outcomes of patient care by ensuring that treatment recommendations are based on the best available evidence. The simple provision of guidelines, however, does not ensure fidelity or guarantee their uptake and use in surgical practice. Research exploring the(More)
BACKGROUND Total hip replacement for end stage arthritis of the hip is currently the most common elective surgical procedure. In 2007 about 7.5% of UK implants were metal-on-metal joint resurfacing (MoM RS) procedures. Due to poor revision performance and concerns about metal debris, the use of RS had declined by 2012 to about a 1% share of UK hip(More)
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